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The adipose stem cells exosomes will be extracted from adipose stem cells isolated autogenously from the patient to be injected locally into the periodontal pockets in order to evaluate their regenerative effect.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exosomes | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| adipose derived stem cells exosomes | Biological | they are small extracellular vesicles |
|
| Measure | Description | Time Frame |
|---|---|---|
| change in gingival inflammation | Gingival index (GI) | 0, 3 and 6 months |
| change in pocket depth | Probing depth (PD) | 0, 3 and 6 months |
| change in attachment level | Clinical attachment level (CAL) | 0, 3 and 6 months |
| change in Bone level | Cone beam C.T (CBCT) | 0 and 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ebtehal Mohammed, Ph.D | Contact | 01224336896 | ebtehalmaawad@dent.bsu.edu.eg, | |
| Noha Saleh, Ph.D | Contact | noha.saleh@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Ebtehal Mohammed, Ph.D | Lecturer of Oral Medicine , Oral diagnosis and Periodontology , Faculty of Dentistry, Beni- Suef University. | Principal Investigator |
| Nesrine Mohammed Khairy, Associated Professor | Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beni-Suef University | Recruiting | Banī Suwayf | 62511 | Egypt |
the data will be published
the data will be available after at least one year
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| ID | Term |
|---|---|
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| Study Director |
| Noha Saleh Mohammed, Associated | Oral and Maxillofacial Radiology, Faculty of Dentistry, Cairo University. | Study Director |
| Dina Sabry, Professor | Biochemistry, Faculty of Medicine, Cairo University | Study Director |
| Cairo University | Recruiting | Cairo | 11562 | Egypt |
|