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Several studies investigating Tai Chi for hypertension have been carried out. However, investigators found the results were in high heterogeneity and poor methodological quality. Thus, investigators intend to provide high quality of the effectiveness and safety of Tai Chi for essential hypertension.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tai Chi | Experimental | 3 sessions of Tai Chi per week for 12 weeks |
|
| Walking | Active Comparator | 3 sessions of walking per week for 12 weeks |
|
| Waiting-list | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tai Chi | Behavioral | Tai Chi is a traditional Chinese mind-body exercise, which combines deep-breath relaxation and gentle movements in sequence with meditation. Each session of Tai Chi will last 60 minutes, including a 10-minute warm-up, a 40-minute Tai Chi practice and a 10-minute cool-down. |
| Measure | Description | Time Frame |
|---|---|---|
| average 24-h Systolic Blood Pressure (SBP) | change from baseline to 12 weeks after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| average SBP and average Diastolic Blood Pressure (DBP) | average SBP and average DBP during the daytime and night-time | baseline, after intervention(12 week), after follow-up(24 week) |
| change of serum concentrations of Nitric Oxide |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rongjiang Jin, PhD | Contact | 13808072058 | cdzyydxjrj@126.com | |
| Juan Li, PhD | Contact | 785939016@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Youping Liu, PhD | Chengdu University of Traditional Chinese Medicine | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Affiliated Hospital of Chengdu University of Traditional Chinese Medicine (Sichuan Provincial Hospital of Traditional Chinese Medicine) | Chengdu | Sichuan | 610075 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33413354 | Derived | Li Y, Zhong D, Dong C, Shi L, Zheng Y, Liu Y, Li Q, Zheng H, Li J, Liu T, Jin R. The effectiveness and safety of Tai Chi for patients with essential hypertension: study protocol for an open-label single-center randomized controlled trial. BMC Complement Med Ther. 2021 Jan 7;21(1):23. doi: 10.1186/s12906-020-03192-z. |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D026302 | Tai Ji |
| D016138 | Walking |
| ID | Term |
|---|---|
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026241 | Exercise Movement Techniques |
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|
|
| Walking | Behavioral | Each session of walking will last 60 minutes, including a 10-minute warm-up, a 40-minute walking and a 10-minutes cool-down. |
|
| baseline, after intervention(12 week) |
| change of serum concentrations of endothelin | baseline, after intervention(12 week) |
| change of serum concentrations of thromboxane A2 | baseline, after intervention(12 week) |
| change of serum concentrations of vascular endothelial growth factor | baseline, after intervention(12 week) |
| blood pressure measured at home with an upper arm electronic sphygmomanometer | baseline, after intervention(12 week), after follow-up(24 week) |
| Medical Outcomes Study 36-Item Short Form | This scale contains eight dimensions (physical function, role physical, bodily pain, general health, vitality, social function, role emotional, mental health) and two summary components (physical and mental), with score from 0 to 100. High scores indicate a better quality of life. | baseline, after intervention(12 week) |
| D026741 |
| Physical Therapy Modalities |
| D008124 | Locomotion |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
| D015444 | Exercise |
| D009043 | Motor Activity |