Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| K01AA023233 | U.S. NIH Grant/Contract | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| National Institute on Alcohol Abuse and Alcoholism (NIAAA) | NIH |
Not provided
Not provided
Not provided
Not provided
This study evaluates the efficacy as well as psychological and neurobiological mechanisms of mobile-delivered alcohol attentional bias modification among heavy drinking adults.
By testing the efficacy and neurobiological mechanisms of behavior change (MOBC) following attentional bias modification among heavy drinking adults, the proposed study has the potential to unify dual process models and neurobiological models of addiction. The cognitive retraining will be delivered via mobile electronic devices to ensure the cost-effectiveness of these procedures, to allow a large amount of retraining to be delivered in an ecologically valid manner, and to facilitate broad dissemination of such procedures if found to be efficacious. Using an intensive longitudinal experimental design, subjects will be randomly assigned into one of 2 groups (attentional bias modification vs. attentional bias control). Ecological momentary assessment (EMA) data will be used to assess changes in cognitive and behavioral measures in situ, and functional magnetic resonance imaging (fMRI) scans before and after cognitive retraining will be used to examine neural changes in specific regions of interest (ROI).
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Attentional Bias Modification | Experimental | Participants complete attentional bias modification using a dot probe task on a mobile device up to 5 times per day for a 28-day period (80 trials per assessment). |
|
| Attentional Bias Control | No Intervention | Participants complete attentional bias assessment-only using a dot probe task on a mobile device up to 5 times per day for a 28-day period (80 trials per assessment). |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Attentional Bias Modification | Behavioral | Mobile-Delivered Cognitive Retraining Intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| Alcohol Use Frequency | Number of days of alcohol use during the 4-week ecological momentary assessment period | 4 weeks |
| Alcohol Use Quantity | Number of standard drinks per day during the 4-week ecological momentary assessment period | 4 weeks |
| Negative Alcohol-Related Consequences | Number negative consequences experienced 4-week ecological momentary assessment period | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Attentional Bias to Alcohol | Measured with the Alcohol Dot Probe Task | 4 weeks |
| Alcohol Cue-Induced Neural Reward Circuit Activation | Regions of interest include ventral tegmental area, dorsal and ventral striatum |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Center on Alcoholism, Substance Abuse, & Addictions | Albuquerque | New Mexico | 87106 | United States | ||
De-identified data will be shared with other researchers.
Not provided
Data can be requested from the PI by October 2020
Data will be shared with qualified scientists who enter a data sharing usage agreement
Not provided
Not provided
Not provided
Not provided
Not provided
Participants are not informed about the nature of the mobile-delivered intervention or their assignment to the intervention or control condition.
| 4 weeks |
| Mind Research Network |
| Albuquerque |
| New Mexico |
| 87106 |
| United States |