Standardizing Method and Development of Normal Values to Measure Human Small Intestinal and Colonic Permeability

Standardizing Method and Development of Normal Values to Measure Human Small Intestinal and Colonic Permeability

To develop a test to measure small bowel and colonic permeability.

The study consists of a physical examination, standardized meals and 3 oral sugar tests with 24 hour urine collections. It requires the participants to visit the Clinical Research Trials Unit in the Charlton Building and Domitilla Building. Remuneration will be offered.

Inclusion Criteria:

• Healthy
• Non-Obese
• Non-pregnant
• Caucasian
• BMI <30kg/m2

Exclusion Criteria:

• Diabetes
• Hypertension
• BMI ≥30kg/m2
• Chronic NSAID use (>3 days/week)