Genetic Characteristics of Metastatic Breast Cancer Patients

Genetic Characteristics of Metastatic Breast Cancer Patients

Genomic analysis for metastatic breast cancer(MBC) patients

• Participant (Inclusion criteria)

  1. Patients who diagnosed metastatic/stage IV breast cancer
  2. Patients who were not received treatment for metastatic breast cancer on palliative setting

• Process

  (1) Tissue/ Blood sample

• At diagnosis, MBC tissue / blood sample (20cc) will be obtained.

• At disease progression after 1st line treatment for MBC, blood sample (20cc) will be obtained (tissue; optional)

  (2) WES, RNASeq, ctDNA, Exosome

• We will analyze genomic characteritics using WES, RNASeq, ctDNA, Exosome.

Inclusion Criteria:

• Patients who diagnosed ad metastatic breast cancer
• Patients who were not received treatment on palliative setting

Exclusion Criteria:

• Patients who did not agree this study
• Patients who did not have any pathologic specimen at MBC diagnosis.