Monitoring of Piperacillin-Tazobactam and Meropenem Plasmatic Levels in Critical Patients

Monitoring of Piperacillin-Tazobactam and Meropenem Plasmatic Levels in Critical Patients

The aim of this study is to establish the Piperacillin-Tazobactam and Meropenem Plasmatic Levels to know if it´s necessary to make some adjustment in the recommended dose regimen.

Inclusion Criteria:

• Patients above 18 years old.
• Hospitalized in the Intense Care Unit.
• Patients treated with Piperacillin-Tazobactam or Meropenem.
• Septic shock.
• Renal hyper clearance.
• Gram-negative bacillary bacteremia.
• Continuous renal replacement technique.
• ECMO.
• Obesity (BMI> 40).

Exclusion Criteria:

• Patients under 18 years old.
• Pregnant women.