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| Name | Class |
|---|---|
| Beijing Shijitan Hospital, Capital Medical University | OTHER |
| Xuanwu Hospital, Beijing | OTHER |
| Beijing Changping Hospital | UNKNOWN |
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Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment. After decades of development, open lumbar decompression and fusion surgery has been the standard treatment. However, there are still people and conditions that cannot be covered, such as elderly people who intolerable surgery, severe osteoporosis, and re-stenosis at adjacent segments after fusion. Percutaneous spinal endoscopic lumbar spinal decompression technique could be performed under local anesthesia, soft tissue damage is minimized, and effective spinal decompression can be achieved. There are still some controversial points of LSS decompression under percutaneous endoscope surgery, such as the range of decompression, choice of approach, postoperative spinal stability, learning curve, surgical safety, long-term effects of endoscopic treatment of restenosis at adjacent segments after fusion surgery. The purpose of this study was to solve these controversial points. A multi-center, prospective registration study based on the real world is planned. The total sample size is about 600 cases (300 cases in endoscopic surgery group, 300 cases in open decompression and fusion group). The mid- to long-term clinical efficacy and safety were evaluated.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Percutaneous endoscopic surgery group | Other |
| |
| Open decompression and fusion surgery group | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Two different treatment | Procedure | One group treated by percutaneous endoscopic surgery. The another group treated by open decompression and fusion surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| Modified MacNab criteria | 1 years after surgery | |
| Visual Analog Scale (VAS) | VAS of leg and back | at 1 years after surgery |
| Oswestry Disability Index(ODI) | at 1 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Range of motion(ROM) | ROM of operated level | at 1 years after surgery |
| Adjacent Segment Disease | Measured on CT and MRI | at 1 years after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bin Zhu, M.D | Contact | 15201278112 | liuxgspine@126.com |
| Name | Affiliation | Role |
|---|---|---|
| Xiaoguang Liu, M.D.,Ph.D. | Peking University Third Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University Third Hospital | Recruiting | Beijing | Beijing Municipality | 100000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35624443 | Derived | Zhai S, Zhao W, Zhu B, Huang X, Liang C, Hai B, Ding L, Zhu H, Wang X, Wei F, Chu H, Liu X. The effectiveness of percutaneous endoscopic decompression compared with open decompression and fusion for lumbar spinal stenosis: protocol for a multicenter, prospective, cohort study. BMC Musculoskelet Disord. 2022 May 27;23(1):502. doi: 10.1186/s12891-022-05440-4. |
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| ID | Term |
|---|---|
| D013130 | Spinal Stenosis |
| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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