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This is a multi-center, randomized, double-blind, placebo-controlled phase 2 study in subjects 8 years of age and older who present with verruca vulgaris (common warts) and desire treatment. Subjects may have up to a total of 6 common warts located on their trunk or extremities that will be treated with study medication and followed throughout the study protocol therapy. All warts will be treated two times per day (BID) for12 weeks. Approximately 90 subjects will be enrolled in this study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| VBP-245 | Experimental | Topical 2% Povidone-Iodine Gel |
|
| Control | Placebo Comparator | Placebo Gel (no Povidone-Iodine) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| VBP-245 | Drug | 2% Povidone-Iodine Gel |
| |
| Placebo Gel (no Povidone-Iodine) |
| Measure | Description | Time Frame |
|---|---|---|
| Decrease in wart diameter (mm) | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Resolution of wart | Wart diameter = 0 mm | 12 weeks |
| Application Site Reaction Adverse Events | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Samuel Barone, MD | Veloce BioPharma LLC | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Veloce BioPharma Clinical Trial Site | Hunt Valley | Maryland | 21030 | United States | ||
| Veloce BioPharma Clinical Trial Site |
Aggregate data will be shared with study investigators.
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| ID | Term |
|---|---|
| D014860 | Warts |
| ID | Term |
|---|---|
| D030361 | Papillomavirus Infections |
| D004266 | DNA Virus Infections |
| D014777 | Virus Diseases |
| D007239 | Infections |
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| Drug |
Placebo Gel (no Povidone-Iodine) |
|
| Plymouth Meeting |
| Pennsylvania |
| 19462 |
| United States |
| Veloce BioPharma Clinical Trial Site | Sugarloaf | Pennsylvania | 18429 | United States |
| Veloce BioPharma Clinical Trial Site | Upper Saint Clair | Pennsylvania | 15241 | United States |
| Veloce BioPharma Clinical Trial Site | Fort Mill | South Carolina | 29708 | United States |
| Veloce BioPharma Clinical Trial Site | Arlington | Virginia | 22209 | United States |
| Veloce BioPharma Clinical Trial Site | Lynchburg | Virginia | 24501 | United States |
| D017193 |
| Skin Diseases, Viral |
| D014412 | Tumor Virus Infections |
| D012874 | Skin Diseases, Infectious |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |