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Multiple sclerosis is a chronic and highly disabling disorder with considerable social impact and economic consequences. It is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. Different areas are affected, including upper airway function, trunk motor control and cardiorespiratory performance. The aim of this study was to determinate the relevance of trunk motor control in upper airway function and cardiorespiratory performance in patients with multiple sclerosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | |||
| Multiple sclerosis group | |||
| Multiple sclerosis trunk impairment |
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| Measure | Description | Time Frame |
|---|---|---|
| Trunk motor control | The impairment of trunk motor control was measured with the Modified Trunk Impairment Scale (mTIS). The values range to 0 from 16 being higher values, better trunk motor control. | baseline |
| Swallowing function | To evaluate swallowing function we used two questionnaires: the Swallowing quality of life questionnaire (SWAL-QOL). It contains 44 items and each item was scored from zero (the worst state) to four (the best state). | baseline |
| Swallowing function | To evaluate swallowing function we used two questionnaires: the Eating Assessment Tool-10 (EAT-10). The values range from 0 to 4 being higher values worse swallowing function. | baseline |
| Ventilation function | Ventilation capacity was measured with spirometry and peak flow using Spirobank II (MIR, Italy). | baseline |
| Phonation function | The phonatory function and it´s repercussion on daily life was evaluated by the Voice handicap index (VHI-30), | baseline |
| The exercise capacity focussed on lower limbs | The Five-Times-Sit-to-Stand test (5STS) | baseline |
| The exercise capacity focussed on upper limbs | The exercise capacity focussed on upper limbs was measured by the unsupported upper-limb exercise test (UULEX) |
| Measure | Description | Time Frame |
|---|---|---|
| Psychological status | Psychological status was evaluated with and the Beck Depression Inventory (Beck) to measure depression. The values range to 0 from 63, being higher values, most severe depression. | baseline |
| Psychological status |
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Inclusion Criteria:
Exclusion Criteria:
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Inclusion Criteria:
Exclusion Criteria:
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marie Carmen Valenza, PhD | Contact | 958248035 | cvalenza@ugr.es |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Healthy Sciences | Recruiting | Granada | 18016 | Spain |
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| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
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| baseline |
| The anaerobic threshold | Incremental sit-to-stand test (ISTS) | baseline |
Psychological status was evaluated with the Beck Anxiety Inventory (BAI) to measure anxiety. The values range to 0 from 63, being higher values, most severe anxiety.
| baseline |
| The degree of neurological functioning | The degree of neurological functioning in patients with MS was measured with the Kurtzke Expanded Disability Status Scale (EDSS). The values range to 0 from 10, being 0 normal status healthy and 10 the death. | baseline |
| The impact of the multiple sclerosis disease | The impact of the disease was determinate with the Multiple Sclerosis Impact Scale (MSIS-29). It´s an instrument with 20 physical items and 9 psychological items. | baseline |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |