Dietary Fibre and Chromium Picolinate Efficacy in Overweight and Obese Women

Impact of Dietary Fibre and Chromium Picolinate on Satiety, Satiation, Weight Loss and Gut Microbiome Composition in Overweight and Obese Women

Obesity is one of the greatest causes of preventable morbidity and mortality worldwide with the main treatments requiring significant changes to lifestyle, particularly dieting and physical exercise. Glucomannan is a dietary fibre that expands in the stomach, creating the feeling of fulness, while chromium can regulate insulin response.

The aim of this pilot study was to investigate the effect of agglomerated glucomannan, oligofructose and chromium, as part of a calorie restricted diet plan, on weight loss, satiety, satiation, mood and gut microbiome composition in a human intervention study.

Inclusion Criteria:

• healthy female
• aged 18-65 years
• with a BMI between 25 and 35 kg/m2
• not dieting within the previous four months
• not having lost > 5% body weight in the previous year
• not having increased physical activity levels in the past 2-4 weeks
• intending to modify them during the study
• able to eat most everyday foods

Exclusion Criteria:

• BMI < 25 kg/m2
• > 35 kg/m2
• significant health problems
• taking any medication or supplements known to affect appetite
• weight within the past month and/or during the study
• pregnant, planning to become pregnant or breastfeeding
• history of anaphylaxis to food
• known allergies or intolerance to foods and/or to the study materials or any of their stated ingredients.
• Volunteers who were on specific food avoidance diets
• with abnormal eating behaviour
• receiving systemic or local treatment likely to interfere with the evaluation of the study parameters
• smokers and those who have recently ceased smoking
• Volunteers who work in appetite or feeding related areas volunteers who participated in another experimental study or receipt of