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| Name | Class |
|---|---|
| Genome British Columbia | INDUSTRY |
| Genome Canada | OTHER |
| Dynacare Laboratories, Inc. | UNKNOWN |
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This project addresses the problem of adverse drug reactions in the three most frequently prescribed therapeutic classes of drugs in children: antibiotics, analgesics, and mental health medications.
We will conduct pilot testing of a pharmacogenomic testing panel and study how the tests and generated test results are utilized and understood by physicians, pharmacists, patients and their families.
The specific objectives are to:
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| Measure | Description | Time Frame |
|---|---|---|
| 150 participants on analgesics, anti-infectives and psychotropics will be given pharmacogenomic recommendations for the risk of gene related adverse events prior to or during treatment. | We will be able to determine the barriers and facilitators of the implementation of the pharmacogenomic service in a health care facility. This will be done by using standardized questionnaires after each pharmacogenomic report is issued. The prescriber and the patient will both answer questions about the utility of the genetic results, the format of the report and the clarity of the content. Results will be recorded and summarized every 25 patients in order to improve the service and the recommendations through the study. | June 2020 |
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Inclusion Criteria:
Exclusion Criteria:
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Any individual who is currently on an analgesic, antibiotic and/or mental health medication that is part of the panels.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bruce Carleton, PharmD. | Contact | 604-875-2179 | bcarleton@popi.ubc.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Children's and Women's Health Centre of British Columbia | Recruiting | Vancouver | British Columbia | V6H 3V4 | Canada |
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| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
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DNA samples will be retained for genomic analyses.
| Children's Hospital of Eastern Ontario | Recruiting | Ottawa | Ontario | K1H 8L1 | Canada |