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| ID | Type | Description | Link |
|---|---|---|---|
| R01GM042725 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of General Medical Sciences (NIGMS) | NIH |
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Using immersive virtual reality as a form of pain distraction during a brief "painful but tolerable" temperature.
This study will use Quantitative Sensory Testing (computer-controlled brief 10 second thermal pain stimuli) in healthy college students.
The primary aim is to conduct a randomized, controlled study with healthy volunteers to explore whether interacting with virtual objects in VR via a high tech interactive VR system makes VR significantly more effective/powerful compared to a less immersive passive VR system, vs. No VR, for reducing pain during quantitative sensory testing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | No Intervention | No treatment, side study to test the assumptions of our quantitative sensory testing pain paradigm | |
| Low Tech/passive Virtual Reality first | Active Comparator | Low Tech VR first brief test phase thermal stimulus + High Tech VR during a second test phase pain stimulus |
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| High Tech/interactive Virtual Reality first | Experimental | High Tech/Interactive VR during first brief test phase thermal stimulus + Low Tech VR during a second brief thermal stimulus. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Virtual Reality psychological pain reduction | Behavioral | attention distraction |
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| Measure | Description | Time Frame |
|---|---|---|
| participants rating of "worst pain " | using a single graphic rating scale, 0 = no pain, 10 = excruciating pain | immediately after each single 10 second test phase quantitative sensory test stimulus during a single visit |
| Measure | Description | Time Frame |
|---|---|---|
| participants rating of "time spent thinking about pain" | using a single graphic rating scale, 0 = none of the time, 10 = all of the time | immediately after each single 10 second quantitative sensory test stimulus during a single visit |
| participants rating of "pain unpleasantness " |
| Measure | Description | Time Frame |
|---|---|---|
| participants rating of "fun" | using a single graphic rating scale, 0 = no fun, 10 = extremely fun. | immediately after each single 10 second quantitative sensory test stimulus during a single visit |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hunter Hoffman, PhD | University of Washington | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Washington (public not eligible for participation) | Seattle | Washington | 98195 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34021173 | Derived | Hoffman HG. Interacting with virtual objects via embodied avatar hands reduces pain intensity and diverts attention. Sci Rep. 2021 May 21;11(1):10672. doi: 10.1038/s41598-021-89526-4. |
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undecided
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| ID | Term |
|---|---|
| D059787 | Acute Pain |
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Within subjects crossover design, VR treatment order randomized (some participants receive Low Tech VR + High Tech VR, some participants receive High Tech VR + Low Tech VR) and some participants receive No VR in a side study to test the assumptions of our QST testing pain paradigm.
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Some of the instructions for the outcome measure will be presented to the participants via a computer.
using a single graphic rating scale, 0 = no pain, 10 = excruciating pain |
| immediately after each single 10 second quantitative sensory test stimulus during a single visit |
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009422 | Nervous System Diseases |