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This study is for verification of predictive biomarkers for pancreatic cancer treatment using multi-center liquid biopsy.
Clinical applicability of KRAS mutations using circulating-tumor DNA in pancreatic cancer patients.
Discovery of biomarkers for predicting pancreatic cancer prognosis through ctDNA panel.
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| Measure | Description | Time Frame |
|---|---|---|
| Clinical applicability of KRAS mutations | Clinical applicability of KRAS mutations using circulating-tumor DNA in pancreatic cancer patients. | Locally advanced and Resectable patients: Pre Treatment, 1,2,3,6,9,12,15,18,21,24months/ Metastatic patients: Pre Treatment, 1,2,4,6,8,10,12,14,16,18,20,22,24 months |
| Discovery of biomarkers through ctDNA panel | Discovery of biomarkers for predicting pancreatic cancer prognosis through ctDNA panel. | Locally advanced and Resectable patients: Pre Treatment, 1,2,3,6,9,12,15,18,21,24months/ Metastatic patients: Pre Treatment, 1,2,4,6,8,10,12,14,16,18,20,22,24 months |
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Inclusion Criteria:
Exclusion Criteria:
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Inpatient or outpatient
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| Name | Affiliation | Role |
|---|---|---|
| Sangmyung Woo, MD | National Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NATIONAL CANCER CENTER 323, Ilsan-ro, Ilsandong-gu, | Goyang-si | Gyeonggi-do | 410-769 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40509918 | Derived | Chun JW, Lee DE, Kim MK, Hwang JH, Lee SH, Jung MK, Kim EJ, Ahn DW, Kim YH, Han SS, Park SJ, Lee WJ, Woo SM, Kong SY. Optimal Value of Mutant KRAS Circulating Tumor DNA for Predicting Prognosis and Monitoring in Patients with Pancreatic Adenocarcinoma: A Prospective Multicenter Cohort Study. Clin Chem. 2025 Sep 3;71(9):993-1004. doi: 10.1093/clinchem/hvaf066. |
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Blood samples