Every lunar year, during the month of Ramadan, Muslims abstain from food and drink between dawn and nightfall. People with type 2 diabetes who fast during Ramadan are at an increased risk of acute glycemic complications. Our aim is to investigate the effect of dosage reduction of four glucose-lowering multidrug regimens on the incidence of acute glycemic complications in people with type 2 diabetes who fast during Ramadan.

Inclusion Criteria:

• Prospective participant is a returning patient with type 2 diabetes;
• Prospective participant expressed an intention to fast during Ramadan;
• Prospective participant has been compliant with one of four glucose-lowering multidrug regimens for at least the past three months.

Exclusion Criteria:

• Prospective participant is a pregnant, postpartum, breastfeeding, or eumenorrheic woman;
• Prospective participant has experienced diabetic ketoacidosis or hyperosmolar hyperglycemic state within three months;
• Prospective participant has received niacin or corticosteroids within one month; and,
• Prospective participant has any history of recurrent hypoglycemia, hypoglycemia unawareness, chronic renal insufficiency (stages IV or V), liver cirrhosis, uncontrolled epilepsy, depressive disorder, bipolar disorder, psychotic disorder, or cognitive dysfunction.