Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose Tissue

Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose Tissue

Researchers are trying to better understand the relationship between inflammation in adipose tissue (AT) and insulin resistance.

Inclusion Criteria:

• Adults ages 30-50 years
• Non-smokers
• Lean subjects with a BMI of 25 or less, gender specific normal body fat,
• Obese, non-diabetic subjects with a BMI between 30 and 50 and taking no medications affecting glucose metabolism or lipid metabolism
• subjects scheduled for an elective laparoscopic or laparotomy abdominal surgery

Exclusion Criteria:

• Receiving corticosteroid therapy or have a history of asthma, COPD or atopic syndrome
• taking any biologic treatment for any autoimmune disorder
• Taking any leukotriene receptor antagonist acting medications (ex. Montelukast)
• smoking