Pericapsular Nerve Group Block for Elective Hip Arthroplasty

Pericapsular Nerve Group Block for Analgesia After Hip Arthroplasty: a Randomized Double-Blind, Placebo-Controlled Trial.

This study examine the effect of Pericapsular Nerve Group (PENG) Block on analgesia after elective hip arthroplasty. Half of participants will receive a PENG Block with local anesthetic, while the other half will receive a PENG Block with a placebo.

Optimized analgesia is crucial for early mobilization after hip arthroplasty. Regional anesthesia, like fascia iliaca block or femoral nerve block, have limited indication because of motor blockade whereas local infiltrations analgesia have shown conflicting analgesic efficacy results in hip arthroplasty.

Pericapsular nerve group (PENG) block is a new regional anesthesia technique targeting specifically sensory nerve branches of the hip articulation. It has been originally described in hip fracture patients.

The aim of this study is to evaluate the efficacy of PENG block on analgesia after elective hip arthroplasty.

Inclusion Criteria:

• Elective total hip arthroplasty
• General anesthesia
• Enhanced Recovery Program

Exclusion Criteria:

• American Society of Anesthesiologists (ASA) Score > 2
• Drug allergy
• Significant psychiatric disturbances
• Preoperative opioid use
• Contraindication to acetaminophen, celecoxib, methylprednisolone or tranexamic acid
• Body Mass Index > 40 kg/m²