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Adults with irritable bowel syndrome (IBS) are being randomized to a yogic breathing or control condition. Participants randomized to the yogic breathing group will be asked to complete a 2-minute yogic breathing video 5 to 7 days per week at home for 4 weeks and control group participants will be asked to maintain their current activities. Participants in this group will be given access to the yogic breathing video at the end of the 4-week control period. IBS symptoms and autonomic and vascular function will be assessed at baseline and at the end of week 4 in both groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yogic breathing intervention | Experimental | Participants assigned to this group will complete a 20-minute yogic breathing video at least 5 days per week for 4 weeks. All sessions except the initial yogic breathing session will be completed at home. Participants will complete the first session at Texas State under the supervision of the investigative team for familiarization. |
|
| Control | No Intervention | Participants in the control group will be asked to maintain their current daily activities and will be given access to the yogic breathing video once all follow-up testing has been completed at the end of week 4. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yogic breathing intervention | Behavioral | Yogic breathing will be completed while following a video provided by the investigative team. Breathing practices consist of slow, deep, relaxation breathing and are led by a certified yoga instructor. |
| Measure | Description | Time Frame |
|---|---|---|
| IBS Symptoms | IBS-Symptom Severity Scale will be administered. | Once at baseline |
| IBS Symptoms | IBS-Symptom Severity Scale will be administered. | Once at the end of week 2 |
| IBS Symptoms | IBS-Symptom Severity Scale will be administered. | Once at the end of week 4 |
| Autonomic function | Heart rate variability will be assessed. | Once at baseline |
| Autonomic function | Heart rate variability will be assessed. | Once at the end of week 2 |
| Autonomic function | Heart rate variability will be assessed. | Once at the end of week 4 |
| Autonomic function | Exercise heart rate recovery will be measured. | Once at baseline |
| Autonomic function | Exercise heart rate recovery will be measured. | Once at the end of week 2 |
| Autonomic function |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Stacy D Hunter, PhD | Texas State University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stacy Hunter | San Marcos | Texas | 78666 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34595801 | Derived | Katherine Jurek M, Seavey H, Guidry M, Slomka E, Hunter SD. The effects of slow deep breathing on microvascular and autonomic function and symptoms in adults with irritable bowel syndrome: A pilot study. Neurogastroenterol Motil. 2022 May;34(5):e14275. doi: 10.1111/nmo.14275. Epub 2021 Oct 1. |
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| ID | Term |
|---|---|
| D043183 | Irritable Bowel Syndrome |
| ID | Term |
|---|---|
| D003109 | Colonic Diseases, Functional |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
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Members of the investigative team will be blinded to the participant's group assignment until all testing is completed.
Exercise heart rate recovery will be measured.
| Once at the end of week 4 |
| Microvascular function | Laser Doppler flowmetry at baseline and in response to local heating will be measured. | Once at baseline |
| Microvascular function | Laser Doppler flowmetry and in response to local heating will be measured. | Once at the end of week 4 |
| D004066 | Digestive System Diseases |