Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 2017/2617 | Other Identifier | CSET number (Gustave Roussy ID) |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Compare patients' feelings in terms of swallowing ability assessed by the overall score of MD Anderson Dysphagia Inventory (MDADI) 2 years after starting treatment between patients who have been treated with IMRT and those who were treated by transoral surgery for a squamous cell carcinoma of the early stage oropharynx.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Radiotherapy | IMRT on the primitive site and the lymph nodes. +/- Concomitant chemotherapy at the discretion of the meeting multidisciplinary |
| |
| Surgery | transoral resection of the primary tumor, with cervical lymph node dissection. Radiotherapy complementary according to the histological criteria of severity |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| transoral resection | Procedure | The technique of transoral surgery will be left to the choice of the surgeon according to the equipment and the experience of the team and will be gathered. The options are: transoral surgery robot-assisted, endoscopic laser transoral surgery, transoral laser surgery classical instruments. The exact description of the resected area will be collected. of the cross-sections will be made for extemporaneous analysis if necessary in lateral margins and deep until complete excision. |
| Measure | Description | Time Frame |
|---|---|---|
| MD Anderson Dysphagia Inventory (MDADI) global score | Score goes from 20 to 100. A higher score means a better ability to swallow | 2 years after inclusion |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
patients who have been treated with IMRT and those who were treated by transoral surgery for a carcinoma squamous cell of the early stage oropharynx
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Philippe Gorphe, MD | Contact | +33 (0)1 42 11 42 11 | philippe.gorphe@gustaveroussy.fr | |
| Thibaud Motreff | Contact | +33 (0)1 42 11 42 11 | thibaud.motreff@gustaveroussy.fr |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gustave Roussy | Recruiting | Villejuif | Val De Marne | 94800 | France |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| IMRT | Radiation | Intensity modulation radiotherapy (RCMI or IMRT) will be performed using techniques static or rotational (arctherapy, tomotherapy). Restraint is recommended with thermoformed mask |
|
| Centre Hospitalier InterCommunal | Recruiting | Créteil | 94000 | France |
|
| Centre Oscar Lambret | Recruiting | Lille | 59000 | France |
|
| Hôpital la Croix Rousse | Recruiting | Lyon | 69004 | France |
|
| Centre Léon Bérard | Recruiting | Lyon | 69008 | France |
|
| CHU Conception | Recruiting | Marseille | 13005 | France |
|
| CHU Montpellier | Recruiting | Montpellier | 34090 | France |
|
| CHU Nantes - Hôtel Dieu | Recruiting | Nantes | 44000 | France |
|
| Institut Universitaire de la face et du cou | Recruiting | Nice | 06100 | France |
|
| Hôpital Européen Georges Pompidou | Recruiting | Paris | 75015 | France |
|
| CHU Reims | Recruiting | Reims | 51100 | France |
|
| Hôpital Charles Nicolle | Recruiting | Rouen | 76000 | France |
|
| CHU Hôpital de Hautepierre | Recruiting | Strasbourg | 67200 | France |
|
| Institut Claudius Regaud | Recruiting | Toulouse | 31100 | France |
|
| CHU Tours | Recruiting | Tours | 37000 | France |
|
| CHRU Nancy - Hôpital de Brabois | Recruiting | Vandœuvre-lès-Nancy | 54500 | France |
|
| ID | Term |
|---|---|
| D002294 | Carcinoma, Squamous Cell |
| ID | Term |
|---|---|
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D018307 | Neoplasms, Squamous Cell |
Not provided
Not provided