Impact of Gamma-OH on Sleep in ICU Patients

Impact of Gamma-OH on Sleep in ICU Patients Difficult to Wean from Mechanical Ventilation

The Main objective of the trial is to assess sleep quality with Gamma-OH® in patients difficult to wean from mechanical ventilation in the ICU.

Inclusion Criteria:

• intubated at least 24 hours
• difficult weaning from mechanical ventilation according to international guidelines, i.e. who failed at least one spontaneous breathing trial.
• Patients will be included after to obtain inform consent.

Exclusion Criteria:

• neuromuscular disease
• central nervous disease
• psychiatric disease
• severe obesity