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Coronavirus
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One of the traditional therapies for restoring the ability of speech in aphasic patients is Melodic Intonation Therapy (MIT), in which everyday phrases are taught in a singing-like manner. The suggested mechanism for speech recovery is that because of the sharing of brain resources for language and music, the regions normally reserved for singing can be trained to help compensate the speech functions originally subserved by the damaged regions. However, this therapy has primarily been applied to speakers of non-tone languages, in which prosodic features carry a more important role than pitch features in conveying meanings. It remains unknown whether MIT will be equally applicable for speakers of tone languages, in which pitch features likely play a more important role. Another uncertainty concerns whether the efficacy of MIT can be extended to patients with expressive speech impairment due to dementia. This pilot study aims to find out the efficacy of MIT for speech-impaired dementia patients in different verbal tasks. The results of this study will provide preliminary empirical evidence to establish the utility of MIT for Cantonese speakers in Hong Kong.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MIT group | Experimental | Subjects will receive the developed Melodic Intonation Therapy. |
|
| Control group | No Intervention | Subjects will not receive any intervention. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Melodic Intonation Therapy (MIT) | Behavioral | Subjects will receive at least 6 MIT sessions in group of 3-5 subjects. In the sessions, experimenter will sing songs with the subjects. Songs used in the intervention are familiar to elderly and are rewritten and embedded with everyday phrases and vocabularies. The whole intervention will span 3-4 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Aphasia Quotient (AQ) in Cantonese Aphasia Battery | Two subtests of the Cantonese Aphasia Battery (auditory comprehension & spontaneous speech) will be executed. Higher AQ means better performance in the respective areas. The minimum of AQ in each subtest is 0, and the maximum is 20. | within a week after procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Change in latency and accuracy in picture naming task | In the computerized picture naming task, subjects are asked to name the objects they see in 52 pictures, within 5000 ms per picture. Visual stimuli of the task are black and white line-drawings. Responses are all recorded for analysis. | within a week after procedure |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| William Shi Yuan Wang, Ph.D. | The Hong Kong Polytechnic University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Elderly homes | Hong Kong | Hong Kong |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 4717723 | Background | Albert ML, Sparks RW, Helm NA. Melodic intonation therapy for aphasia. Arch Neurol. 1973 Aug;29(2):130-1. doi: 10.1001/archneur.1973.00490260074018. No abstract available. | |
| 4452250 | Background | Sparks R, Helm N, Albert M. Aphasia rehabilitation resulting from melodic intonation therapy. Cortex. 1974 Dec;10(4):303-16. doi: 10.1016/s0010-9452(74)80024-9. No abstract available. |
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All the data collected in screening, pre- and post-assessment will not be shared with other researchers.
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| ID | Term |
|---|---|
| D003704 | Dementia |
| D003147 | Communication Disorders |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D019965 | Neurocognitive Disorders |
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|
| Change in performance of semantic fluency task |
In the computerized semantic fluency task, subjects are given 5 categories (e.g. animals) and asked to name as many members of the categories (e.g. cat, dog) as possible. For each category, they have one minute to respond. All the responses are recorded for analysis. |
| within a week after procedure |
| 30312779 | Result | Sarkamo T, Sihvonen AJ. Golden oldies and silver brains: Deficits, preservation, learning, and rehabilitation effects of music in ageing-related neurological disorders. Cortex. 2018 Dec;109:104-123. doi: 10.1016/j.cortex.2018.08.034. Epub 2018 Sep 19. |
| D001523 | Mental Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D065886 | Neurodevelopmental Disorders |