IgG-4 Levels in Systemic Sclerosis

Comparing IgG-4 Levels in Systemic Sclerosis Patients vs. Healthy Controls

This is an observational - non interventional study. The investigators will compare IgG4 levels of 80 healthy donors (from Israel blood bank - MDA) and 80 Systemic Sclerosis patients from Meir Medical Center.

IgG4 levels will be obtained from medical records of 80 SSc patients between the years 2000-2019. These will be compared to IgG4 levels from sera of 80 healthy donors (from Israel blood-bank - MDA). Correlations between IgG4 levels and the following will be made: age, sex, disease type (limited or diffused SSc), disease duration, medications.

Inclusion Criteria:

• SSc patients

Exclusion Criteria:

• other chronic co-morbidities