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Pantoprazole in Cisplatin Nephrotoxicity
Pantoprazole in Cisplatin NephrotoxicityPantoprazole in Cisplatin Nephrotoxicity. Is it protective?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard hydration alone | Active Comparator | Cisplatin with standard hydration |
|
| Pantoprazole high dose | Active Comparator | Cisplatin with standard hydration with pantoprazole 1.6 mg/kg |
|
| Pantoprazole Low dose | Active Comparator | Cisplatin with standard hydration with pantoprazole 0.6 mg/kg |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pantoprazole low dose | Drug | Pantoprazole 0.6 mg/kg |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of patients with no renal toxicity | The number of patients with no renal toxicity | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sherief Abd-Elsalam, ass. prof. | Contact | 00201147773440 | sheriefabdelsalam@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Eman M Ghonaim, Msc | Demonstrator of Clinical Pharmacy | Principal Investigator |
| Sahar El-Haggar, Prof | Tanta University | Principal Investigator |
| Suzy Goher, Lecturer |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sherief Abd-Elsalam | Recruiting | Tanta | Egypt |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D000077402 | Pantoprazole |
| D002945 | Cisplatin |
| ID | Term |
|---|---|
| D053799 | 2-Pyridinylmethylsulfinylbenzimidazoles |
| D013454 | Sulfoxides |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
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| Pantoprazole high dose | Drug | Pantoprazole 1.6 mg\kg |
|
|
| Standard hydration | Other | Standard hydration alone |
|
|
| Cisplatin | Drug | Cisplatin |
|
| Tanta University |
| Principal Investigator |
| D011725 |
| Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D001562 | Benzimidazoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
| D017672 | Nitrogen Compounds |
| D017671 | Platinum Compounds |