The study aimed to analyze the compatibility of Qnox values with hemodynamic changes as a predictor of pain response in tracheal intubation procedures

Fifty-four patients were given informed consent before enrolling the study. Non-invasive blood pressure monitor, electrocardiogram, pulse oxymetry, and Conox probe were set on the subjects in the operation room. Baseline hemodynamic is noted. General anesthesia induction was done by fentanyl 2.5 mcg/kg and propofol 2 mg/kg. Endotracheal tube intubation was facilitated with rocuronium 0.8 mg/kg as muscle relaxant. qNox values right before intubation and after intubation is noted, as well as hemodynamic changes in one minute after intubation

Inclusion Criteria:

• patient undergoes general anesthesia with tracheal intubation
• fasting as required for surgery
• physical ASA status I - II
• signing informed consent

Exclusion Criteria:

• patient with difficult airway management
• patient with history of central nervous system abnormalities
• patient with history of hypersensitivity to drugs for general anesthesia

adult patients undergo general anesthesia procedure with tracheal intubation