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The rotational thromboelastogram (ROTEM) test can be performed on patients with placenta previa/accreta/increta/percreta who have a high likelihood of massive bleeding, and the predictors can be identified by comparing the patients who actually show massive bleeding with those who do not.
Applying these predictive factors to pregnant women undergoing cesarean section after diagnosis of placenta previa/accreta/increta/percreta, it will be advantageous for the perioperative management because it is possible to select pregnant women with a factor of massive bleeding.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients with risks of intraoperative massive bleeding | patients with risks of intraoperative massive bleeding |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ROTEM | Diagnostic Test | ROTEM including INTEM, EXTEM, APTEM, and FIBTEM |
|
| Measure | Description | Time Frame |
|---|---|---|
| Blood loss | Volume of intraoperative blood loss | 1 min after finishing an operation |
| Change of INTEM | intrinsic pathway component | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation |
| Change of EXTEM | extrinsic pathway component | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation |
| Change of APTEM | fibrinolytic component | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation |
| Change of FIBTEM | the level of fibrinogen | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation |
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Inclusion Criteria:
Exclusion Criteria:
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Pregnant women over 20 years old who are scheduled for cesarean section under spinal anesthesia after diagnosis of placenta previa/increta/percreta/accreta
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 13620 | South Korea |
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| ID | Term |
|---|---|
| D010923 | Placenta Previa |
| D010921 | Placenta Accreta |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| D010922 | Placenta Diseases |