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Silicosis, a preventable yet irreversible occupational lung disease, has an insidious onset with a latency period for diagnosis extending beyond 10 years from the initial exposure. The central hypothesis of this study is that silicosis cases may currently be going undetected. The long-term goal of this research is to determine the current prevalence and forecast the future prevalence of silicosis and other pneumoconiosis among working populations in Oklahoma and to assist the public health and the healthcare system in planning for a potential resurgence of silicosis.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tuberculosis test | Diagnostic Test | Tuberculosis (TB) test: A blood sample is collected for lab testing to determine if you have tuberculosis (QuantiFeron test). Alternatively, the test is done by injecting a small amount of fluid (called tuberculin) into the skin on the lower part of the arm. A person given the tuberculin skin test must return within 48 to 72 hours to have a trained health care worker look for a reaction on the arm. |
| |
| Chest X-ray | Diagnostic Test | Chest X ray: non-invasive medical test that helps physicians diagnose and treat medical conditions of the lungs and chest. The Chest X-ray will be done to check for abnormalities on the lungs. The test is non-invasive. | ||
| Pulmonary Function Test | Diagnostic Test | A pulmonary function test (PFT, spirometry) is a breathing test that measures how much air your lungs can hold as well as how hard and fast you can blow air out of your lungs. The test is not invasive and involves blowing into a machine. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Estimate of average cumulative respirable crystalline silica exposure (semi-quantitative) | Estimate of average cumulative respirable crystalline silica exposure (semi-quantitative) | Single point assessment at baseline survey |
| Percentage of participants who report any exposure to silica | Percentage of participants who report any exposure to silica | Single point assessment at baseline survey |
| Prevalence of silicosis among study group | Percentage of participants with confirmed diagnosis of silicosis | Single point assessment at clinic visit |
| Measure | Description | Time Frame |
|---|---|---|
| Analysis to determine if any demographic, work history, or other trait correlates with increased silica exposure | Analysis to determine if any demographic, work history, or other trait correlates with increased silica exposure | Single point assessment at baseline survey |
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Inclusion Criteria:
Exclusion Criteria:
Men Male gender identity
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Primary care clinic, community sample
Participants will be recruited from waiting rooms or other common spaces at participating community health clinics.
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| Name | Affiliation | Role |
|---|---|---|
| Jad Kebbe, MD | University of Oklahoma | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | United States |
Researchers may request a deidentified dataset.
The de-identified dataset may be shared between other investigators of the same institution as the PI, in accordance with University and Institutional Review Board policies.
Any investigator not affiliated with the University of Oklahoma Health Sciences Center who desires access to a de-identified dataset may do so by coordinating a Data Use Agreement between the investigator's institution and the PI's institution.
Datasets will only be released with an active Data Use Agreement or other similar agreement with the University of Oklahoma Health Sciences Center.
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2 years after publication
Active Data Use Agreement or other similar agreement with the University of Oklahoma Health Sciences Center
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| ID | Term |
|---|---|
| D012829 | Silicosis |
| D008171 | Lung Diseases |
| D011009 | Pneumoconiosis |
| ID | Term |
|---|---|
| D017563 | Lung Diseases, Interstitial |
| D012140 | Respiratory Tract Diseases |
| D055370 | Lung Injury |
| D009784 | Occupational Diseases |
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| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D012129 | Respiratory Function Tests |
| D013147 | Spirometry |
| ID | Term |
|---|---|
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D003948 | Diagnostic Techniques, Respiratory System |
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