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Deprescribing, the process of safely reducing or discontinuing unnecessary or harmful medication, has the potential to decrease polypharmacy and improve health outcomes. In this study a structured implicit algorithm, focusing on both extrinsic medication factors (eg change in disease) and intrinsic patient factors (eg. pill burden) will be used.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants | Other | The aim of this study is to test the feasibility of this algorithm as an intervention to carry out deprescribing a targeted medication group, proton pump inhibitors (PPI's) and statins, among nursing home residents. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Deprescribing algorithm | Other | For this study an implicit, evidence-supported and patient-centred algorithm has been developed. The outcome of the algorithm is an advice to the doctor to deprescribe or not deprescribe the statin and/or PPI. |
| Measure | Description | Time Frame |
|---|---|---|
| Decrease in pill burden (the number of statins and PPI's) | On T0 (intervention) and on T1 + T2 (3 and 6 months after intervention), we will measure the number of PPI's and statins on the medication list of every participant. These are provided by the pharmacist. | 3 and 6 months after intervention. |
| Decrease in pill burden (the dose of statins and PPI's) | On T0 (intervention) and on T1 + T2 (3 and 6 months after intervention), we will measure the dose of PPI's and statins on the medication list of every participant. These are provided by the pharmacist. | 3 and 6 months after intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| All possible negative side effects of deprescribing (e.g. nausea, symptom recurrence) | All possible negative effects of deprescribing as recognised by the doctor involved, e.g. symptom recurrence. | From intervention to six months after intervention |
| Feasibility to use this algorithm. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jos Schols, Prof. Dr. | Principal Investigator | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lemborgh | Sittard | Limburg | 6135CV | Netherlands |
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A multicentre, unblinded, single group (pre-comparison and post-comparison) feasibility study.
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Three and six months after intervention we will ask the participating doctors the next questions (per included participant):
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| 3 and 6 months after intervention |