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| ID | Type | Description | Link |
|---|---|---|---|
| U48DP006380-01-01 | Other Identifier | Centers for Disease Control and Prevention | |
| U48DP006380-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Centers for Disease Control and Prevention | FED |
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The goal of the proposed Implementation Research project is to assess the feasibility of and pathways for implementation of a virtually-delivered DPP (v-DPP) supported by community-based care coordination facilitated by community health workers (CHWs) and hospital-based community nurses (HCNs). The goal of the intervention is to improve body weight, blood pressure, diet quality, and physical activity levels among low-income individuals at risk for type 2 diabetes.
Specific aims and hypotheses:
Conduct formative research with community partners (via focus groups and interviews with key stakeholders and a small pilot) to assess community, systemic, technology, and structural level barriers to implementation of a virtually-delivered Diabetes Prevention Program.
Hypothesis: These efforts will identify individual and community needs, barriers, and resources affecting the feasibility of v-DPP implementation. In addition, strategies for facilitating the delivery of the v-DPP to low-income communities will be developed.
In collaboration with community partners, utilize strategies identified in Aim A1 to maximize impact of the v-DDP in target communities, as evidenced by measures of reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) and assess factors influencing RE-AIM outcomes (e.g. social determinants of health, demographic variables, self-efficacy).
Hypothesis: The v-DPP facilitated by community-based care coordination will produce favorable RE-AIM outcomes. Factors influencing these outcomes will be explored as well.
Demonstrate improvements in body weight, blood pressure, diet quality, and physical activity in low-income individuals at risk for type 2 diabetes who participate in a v-DPP facilitated by community-based care coordination.
Hypothesis: The v-DPP, facilitated by community-based care coordination provided by CHWs and HCNs, will improve body weight, blood pressure, diet quality, and physical activity levels in the study communities.
Collaborate with community partners to develop and implement a strategic approach to sustain the v-DPP facilitated by community-based care coordination in the study communities and translate it to other community settings.
Hypothesis: The implementation approach will be packaged, including strategies for implementation in different settings and related costs, providing a process for implementation in other low-income communities in our region and nationally.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| vDPP Full Study | Experimental | Participants will take part in a 52 week study receiving the vDPP intervention. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| vDPP | Behavioral | virtual Diabetes Prevention Program |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in BMI | Body mass index (BMI) will be measured as a participant's weight in kilograms divided by his/her height in meters squared. Height will be collected by a RA/CHW/HCN using a stadiometer at baseline and at 4 weeks. | 16 weeks and 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Waist Circumference | Waist circumference in centimeters will be collected at baseline and at 4 weeks. | 16 weeks and 12 months |
| Change in Total Cholesterol | Total cholesterol (Tchol) will be collected at baseline and at 4 weeks. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rafael Perez-Escamilla, PhD | Professor of Public Health, Director of the Office of Public Health Practice, and Director of the Global Health Concentration at the Yale School of Public Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Griffin Hospital | Derby | Connecticut | 06418 | United States | ||
| Yale University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42288862 | Derived | LaMonaca K, Campbell-Britton M, Duffany KO, Comerford BP, Morales SI, Ayettey RG, Astudillo K, Swansiger M, Kidd C, Rue B, Santilli A, Njike VY, McGuire T, Deyling M, Perez-Escamilla R. Community-engaged design of a virtual diabetes prevention program intervention with care coordination. BMC Health Serv Res. 2026 Jun 13. doi: 10.1186/s12913-026-14860-0. Online ahead of print. |
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| 16 weeks and 12 months |
| Change in Triglycerides | Triglycerides (TG) will be collected at baseline and at 4 weeks. | 16 weeks and 12 months |
| Change in High-density Lipoprotein | High-density lipoprotein (HDL) will be collected at baseline and at 4 weeks. | 16 weeks and 12 months |
| Change in Diet Quality | Dietary quality will be assessed at baseline and 4 weeks for the study. Participants will complete a 24-hour dietary recall using a web-based Automated Self-Administered 24-Hour Recall (ASA24) (available from the National Cancer Institute at ttp://riskfactor.cancer.gov/tools/instruments/asa24/), which will guide them through the process of completing the recall. Diet quality based on the information provided will be assessed using the Healthy Eating Index 2010 (HEI-2010). | 16 weeks and 12 months |
| Change in Physical Activity | Physical activity level (PA) will be assessed at baseline and 4 weeks for the study. The International Physical Activity Questionnaire (IPAQ). It is a comprehensive tool containing information on weekly household and yard-work activities, occupational activity, transport, leisure time physical activity, and sedentary behavior. | 16 weeks and 12 months |
| New Haven |
| Connecticut |
| 06510 |
| United States |