The ANM is the first initiative that puts advanced pharmaceutical care into practice in Andalusia (Spain). The aim of this is study is to evaluate the effectiveness of the intervention Assistance to New Medicines (ANM) in the improvement of adherence to treatment in community pharmacies.

Design: parallel cluster pragmatic randomized controlled trial. The study includes patients users of a community pharmacies, who meet the following inclusion criteria: patient who starts treatment of any of the following pathologies: Chronic Obstructive Pulmonary Disease (COPD), Arterial Hypertension or Diabetes Mellitus in Andalusia (Spain).

In order to avoid possible contamination between patients assigned to the control and intervention group, randomization will be carried out at the pharmacy level; preventing the pharmacist from applying part of the intervention to the control group.

Interventions: patients randomized: (i) current practice; or (ii) ANM intervention thru a pharmacist delivered support for a newly prescribed medicine.

Inclusion Criteria: patient who starts treatment of any of the following diseases:

• Chronic Obstructive Pulmonary Disease (COPD).
• Arterial Hypertension
• Diabetes Mellitus.
• Anticoagulants

Exclusion Criteria:

• those users who do not know how to read and write in Spanish,
• Suffer from a physical or mental disorder that makes it impossible to perform the

The statistical analysis will be performed by a person who would be blinded to which arm were assigned the subjects.