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| Name | Class |
|---|---|
| University of Pittsburgh | OTHER |
| The Cooper Health System | OTHER |
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The investigators are interested in studying why experienced clinicians make specific decisions regarding the monitoring of patients' physiological states and why clinicians might make decisions that are contrary to current best practices or known evidence. More generally, the program objective is to refine and validate a novel methodology to delineate clinicians' decision-making strategies. More specifically, the investigators will study the decision to reverse neuromuscular blockade at the end of an anesthetic. This clinical decision will be studied in this project because: 1) it has been well documented that a substantial percentage of practitioners do not follow best practices; 2) the variables are relatively circumscribed and well described; and 3) it can be framed as a binary decision.
The investigators propose to conduct an observational mixed-methods study developing and using clinical vignettes and cognitive interviews to better understand the decision-making approaches and preferences of clinically active anesthesia providers with regard to their decision-making during clinical anesthesia cases. After developing clinical vignettes and related questions, the investigators will first obtain detailed demographic and clinical practice variables from the participants via a survey. Participants will then review multiple vignettes that present different clinical situations that focus on decisions to reverse neuromuscular blockade and/or extubate the patient. Each participant will provide their decisions for each vignette. The investigators will then conduct an audiotaped interview, using cognitive task analysis methods, to ascertain the factors that played a role in these decisions.
The investigators propose to conduct a 3-site prospective observational mixed-methods study using clinical vignettes and cognitive interviews to better understand the decision making approaches and preferences of practicing community anesthesiologists with regard to the management of non-depolarizing neuromuscular blockade (NMB) at the end of general endotracheal anesthesia cases.
The objectives of this initial study is to begin to understand:
2.1.2. Study Hypotheses
For this initial study, the investigators hypothesize that:
This will be a remotely conducted national prospective observational simulation study of 36 experienced community anesthesiologists using a clinical vignette and cognitive interviews to better understand the decision making approaches and preferences of practicing community anesthesiologists with regard to the management of neuromuscular blockade (NMB) at the end of general endotracheal anesthesia cases.
Cognitive interview transcript coders and analysts will be blinded to the identity and attributes of the participants.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Anesthesia Providers | Clinically active anesthesia providers |
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| Measure | Description | Time Frame |
|---|---|---|
| Accuracy on 9-item NMMR Knowledge Test | Percent correct on 9-item test of evidence-based knowledge about neuromuscular monitoring and reversal | Day of enrollment only |
| Confidence in NMMR Knowledge | % confidence (0-100) in the correctness of participant's response on the knowledge test | Day of enrollment |
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Inclusion Criteria:
Exclusion Criteria:
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Clinically active anesthesia providers
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville | Tennessee | 37203 | United States |
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154 recruited for survey, 36 of these were interviewed.
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| ID | Title | Description |
|---|---|---|
| FG000 | Anesthesia Providers | Clinically active anesthesia providers who answered the survey |
| Title | Milestones | Reasons Not Completed | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
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Clinically active anesthesiologists
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| ID | Title | Description |
|---|---|---|
| BG000 | Anesthesia Providers | Clinically active anesthesia providers |
| Units | Counts |
|---|---|
| Participants |
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| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Median |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Accuracy on 9-item NMMR Knowledge Test | Percent correct on 9-item test of evidence-based knowledge about neuromuscular monitoring and reversal | All survey participants | Posted | Mean | Standard Deviation | Percent | Day of enrollment only |
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Baseline to 8 weeks
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Anesthesia Providers | Clinically active anesthesia providers | 0 |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Matthew B Weinger, MD | Vanderbilt University Medical Center | 615-936-6598 | matt.weinger@vumc.org |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Jun 13, 2023 | Jan 5, 2026 | Prot_000.pdf |
| SAP | No | Yes | No | Statistical Analysis Plan | Sep 16, 2025 | Jan 5, 2026 | SAP_001.pdf |
| ICF | No | No | Yes | Informed Consent Form | Jun 16, 2025 | Feb 11, 2026 | ICF_002.pdf |
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| years |
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| Sex: Female, Male | One individual failed to complete the sex question of the survey | Count of Participants | Participants |
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| Race and Ethnicity Not Collected | Race and Ethnicity were not collected from any participant. | Count of Participants | Participants |
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| Primary | Confidence in NMMR Knowledge | % confidence (0-100) in the correctness of participant's response on the knowledge test | Posted | Mean | Standard Deviation | percent confident | Day of enrollment |
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| 154 |
| 0 |
| 154 |
| 0 |
| 154 |
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