Pancreatic Cancer and Carbon Ion Radiotherapy

Pancreatic Cancer and Carbon Ion Radiotherapy

Irradiation of non-operable pancreatic cancer with carbon ions (C12). This therapy is expected to be more effective than the current Gold Standard of photon irradiation applied in the case of non-operable pancreatic cancer.

Inclusion Criteria:

• Histologically confirmed, inoperable primary or local recurrent pancreatic cancer
• Written informed consent (must be available before enrollment in the trial)
• Karnofsky performance score > 60 or ECOG-status 0/1 (at least: patient should be able to take care of himself, although daily-life activity or work is not possible)
• Age ≥ 18 years

Exclusion Criteria:

• No clear difference between tumor edge and upper gastrointestinal tract in baseline imaging
• Extensive lymphatic metastases
• Disability of subject to understand character and individual consequences of the clinical trial
• Distant metastases
• Previous radiotherapy of the upper abdomen
• Active medical implants (e.g. pacemaker, defibrillator), contradicting radiotherapy at HIT
• Participation in another clinical study or observation period of competing trials, respectively