Effects of SIMEOX on Airway Clearance in Cystic Fibrosis

Effects of the Addition of the SIMEOX Device on Autogenic Drainage in Patients With Cystic Fibrosis

This study will investigate the contribution of SIMEOX technology on the effectiveness of bronchial drainage.

This is a crossover study to evaluate the contribution of SIMEOX on the effectiveness of bronchial drainage (verified by the amount of sputum secretions, the rheology of sputum secretions and the subjective sensation of ease of sputum) in patients with cystic fibrosis.

Patients will perform, in randomized order (1) a 30-min session of autogenic drainage, (2) a 30-min session of autogenic drainage with the SIMEOX device. Sputum will be collected during and after the session. The two sessions will be performed with minimum washout time of 24 hours.

Inclusion Criteria:

• Adults with cystic fibrosis
• Chronic bronchorrhea, able to expectorate by themselves
• Hospitalized

Exclusion Criteria:

• Regular use of SIMEOX,
• Difficulties in understanding instructions,
• Severe cardiac comorbidity.