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| Name | Class |
|---|---|
| Hawaa Fertility Center | OTHER |
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This study aiming to investigate if difference in the timing of cumulus removal post retrieval would have any critical impact on fertilization and embryonic development.
Patients under 37 year old who were treated with controlled ovarian stimulation for ICSI were randomly divided into 2 groups; Group A: Oocytes were denudated immediately after oocyte retrieval , Group B: Oocytes were denudated 2 hours after retrieval and both groups were microinjected at 4 hours from ovum pickup. Microinjection was performed on all matured oocytes only and they were cultured to blastocyst stage.The rates of maturation, fertilization, good quality blastulation, chemical pregnancy and clinical pregnancy were analysed and compared between the two groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A (immediate denudation) | Oocytes were denudated immediately after oocyte retrieval and were microinjected at 4 hours from ovum pickup. Microinjection was performed on all matured oocytes only and they were cultured to blastocyst stage.The rates of maturation, fertilization, good quality blastulation, chemical pregnancy and clinical pregnancy were analysed and compared between the two groups. |
| |
| Group B ( 2hs denudation after ovum pickup) | Oocytes were denudated 2 hours after retrieval and were microinjected at 4 hours from ovum pickup. Microinjection was performed on all matured oocytes only and they were cultured to blastocyst stage.The rates of maturation, fertilization, good quality blastulation, chemical pregnancy and clinical pregnancy were analysed and compared between the two groups. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| denudation time lag | Procedure | The time between ovum pickup and denudation of oocyte |
|
| Measure | Description | Time Frame |
|---|---|---|
| Day 5, good quality blastocyst | Assessment were done according to gardener classification | 120 hour post ovum pickup |
| Measure | Description | Time Frame |
|---|---|---|
| clinical pregnancy | Assessment was done by observation of a gestational sac at 6 wks | 6 weeks from the last normal menstrual period |
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Inclusion Criteria:
Exclusion Criteria:
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couples who came seeking fertility through our IVF center
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hawaa Fertility Center | Banhā | Qalyubia Governorate | 13512 | Egypt |
after completion of the study
after 1 year for 2 months
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| ID | Term |
|---|---|
| D007247 | Infertility, Female |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| D000091662 | Genital Diseases |
| D007246 | Infertility |