Butyrophilins Role in Colon Cancer

Role of Butyrophilins in Colon Cancers Aggressiveness Evaluation

quantification of BTNL molecules in colon cancer in order to determinate if their could be used as a prognostic marquer

Inclusion Criteria:

• Patient is older than 18 years old,
• Signed participation consent,
• Non-metastatic colon cancer immediately resectable or metastatic and liver synchronous for which it was decided a combined colic and liver surgery (metastatic patient at the outset) in multidisciplinary consultation meeting.
• Performance Status (PS) 0 or 1
• affiliated to the social security or beneficiary

Exclusion Criteria:

• Rectal cancer, colon cancer recurrence
• Emergency of colon cancer Surgery
• History of inflammatory disease of the digestive tract (Crohn's disease or ulcerative colitis)
• Patient who received neoadjuvant therapy other than chemotherapy
• Patient treated with immune-suppressors or long-course corticosteroids <12 months
• Pregnant women or likely to be pregnant (without effective contraception) or breastfeeding,
• Person in urgent situation, person under legal protection measure, or unable to express his / her consent,
• Impossibility of submitting to the medical examination of the test for geographical, social or psychological reasons