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| Name | Class |
|---|---|
| Belarusian State Medical University | OTHER |
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Treatment of systemic lupus erythematosus with pooled allogenic mesenchymal stem cells
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SLE patients MSC treatment | Experimental | Patients with SLE, who receive pooled mesenchymal stem cells in addition to the standard treatment according to the Clinical protocols |
|
| SLE patients standard treatment | Active Comparator | Patients with SLE, who receive standard treatment according to the Clinical protocols |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pooled mesenchymal stem cell | Biological | Pooled allogenic mesenchymal stem cell derived from olfactory mucosa |
|
| Measure | Description | Time Frame |
|---|---|---|
| Efficacy evaluation | Efficacy evaluation (SELENA-SLEDAI) | 6 month |
| Measure | Description | Time Frame |
|---|---|---|
| Safety eveluation | Absence of adverse reactions | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andrei Hancharou, Dr | Director, the Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Study Director |
| Konstantin A Chizh, Dr | Associate professor, Belarusian State Medical University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Minsk | 220072 | Belarus |
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| Standard treatment according to the Clinical protocols | Other | Standard SLE treatment according to the Clinical protocols approved by the Ministry of healthcare of Republic of Belarus |
|
| ID | Term |
|---|---|
| D008180 | Lupus Erythematosus, Systemic |
| ID | Term |
|---|---|
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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