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Anterior cervical decompression and fusion is the standard procedure for operation of cervical disc herniations. Mobility-preserving Full-Endoscopic Cervical Posterior discectomy is the most common alternative in the case of soft localization of the pathology. Endoscopic techniques are considered standard in many areas, since they may offer advantages in surgical technique and rehabilitation. These days, all disc herniations can be operated in full-endoscopic technique. With the full-endoscopic posterior cervical discectomy a procedures is available for cervical disc operations.
Investigators conducted a differential, randomized, 1:1, double-blind clinical control trial to compare the clinical effect, safety and feasibility of Full-Endoscopic Cervical Posterior discectomy and Anterior cervical decompression and fusion. The study was conducted in three centers at the same time, including the Second Affiliated Hospital of Zhejiang University Medical College, Zhejiang Provincial People's Hospital and Ningbo University Medical College Affiliated Hospital. This study is expected to include 308 patients with single level soft cervical disc herniation.Participants were randomly assigned to different groups for corresponding surgical intervention after complete preoperative evaluation.Participants received a standard 5-year follow-up procedure
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The experimental group | Other | PPECD was performed in the experimental group |
|
| control group | Other | ACDF was performed in the control group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Percutaneous Posterior Endoscopic Cervical Discectomy | Procedure | The most common alternative in the case of soft cervical disc herniations. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Improvement rate | M-JOA Scoring | Follow up for 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Basic information of participants | Age in year, gender in male or female, occupation | Follow up for 5 years |
| Basic information of participants | weight and height will be combined to report BMI in kg/m^2 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| 2nd Affiliated Hospital, School of Medicine, Zhejiang University | Recruiting | Hangzhou | Zhejiang | 310000 | China |
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Participants were unaware of the grouping process. The surgeons were unaware of the grouping process. The follow-up recorders were unaware of the grouping process.
| Anterior cervical decompression and fusion | Procedure | The standard procedure for operation of cervical disc herniations. |
|
| Follow up for 5 years |
| Imaging examination | Cervical cobb angle change i | Follow up for 5 years |
| Pain Assessment | VAS Score | Follow up for 5 years |
| Operation duration | Operation duration in minute | intraoperative |
| Amount of bleeding during operation | Amount of bleeding during operation in milliliter | Follow up for 5 years |
| ID | Term |
|---|---|
| D050939 | Gene Fusion |
| ID | Term |
|---|---|
| D011995 | Recombination, Genetic |
| D055614 | Genetic Phenomena |
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