Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac

Feasibility of Imaging and Radiotherapy on a Novel 1.5 T Hybrid Magnetic Resonance Imaging - Linear Accelerator System (MR-Linac)

This study investigates the feasibility of imaging and treatment on a novel 1.5 T MR-Linac radiotherapy hybrid device.

Novel hybrid devices combine magnetic resonance imaging (MRI) and a linear accelerator in a single device. The superior soft tissue contrast compared with cone-beam computed tomography based treatment and the possibility for daily plan adaptation promise a higher precision of treatment, better target volume coverage and normal tissue sparing. In a first step the present study will test the feasibility of imaging and treatment on the 1.5 T MR-Linac.

Inclusion Criteria:

• existing indication for radiation therapy
• minimum age 18 years, no upper age limit
• capacity for consent
• Informed consent

Exclusion Criteria:

• contraindication for MRI (claustrophobia, metallic implants not applicable for MRI
• pregnancy