Fit for Surgery. Multimodal Prehabilitation in Colorectal Cancer Patients

Fit for Surgery. Clinical Randomized Trial of Multimodal Prehabilitation Strategy in Patients With Colorectal Cancer.

Randomized clinical trial of multimodal prehabilitation in vulnerable patients with colon or rectal cancer prior to surgery.

Fit for surgery is a randomized clinical trial of multimodal prehabilitation prior to colon or rectal cancer surgery. Participants will either receive

The study is a part of the PREHAB study which is performed in collaboration with international centers.

The full protocol are published BMC Cancer. 2019 Jan 22;19(1):98. doi: 10.1186/s12885-018-5232-6.

Inclusion Criteria:

• Undergoing elective colorectal cancer surgery
• WHO performance status I and II
• Signed consent

Exclusion Criteria:

• Known metastatic disease
• Unable to perform baseline test or basic training e.g. paralytic or completely immobilized patients, orthopedic impairments.
• ASA 4 or 5 (American Society of Anesthesiologist Classification)
• Neoadjuvant chemo- or radiation therapy
• Renal failure III B or higher
• Illiteracy or unable to write or understand Danish
• Cognitive disabilities, which affects adherence e.g. severe dementia (MMSE score ≤17).
• Withdrawal of consent.