Pilot Study- Treat to Target Vitamin D in End Stage Renal Disease

Pilot Study- Treat to Target Vitamin D in End Stage Renal Disease

Feasibility of dose adjustment to reach a 6 month 25-hydroxy vitamin D level of 35-50 ng/ml in end stage renal disease patients

Pilot study to test the feasibility of adjusting doses based on a prespecified algorithm to reach a 6 month 25(OH)D level of 35-50 ng/ml in end stage renal disease patients.

Inclusion Criteria:

• likely be able to complete the study, >3 months on hemodialysis, receiving standard of care through their nephrologist.

Exclusion Criteria:

• on peritoneal dialysis, allergy to vitamin D, liver disease, intestinal disorders that interfere with vitamin D absorption, taking vitamin D >800 IU per day, 25(OH)D level >30 ng/ml, glucocorticoids, anticonvulsants or drug therapies for osteoporosis, pregnancy.