Metabolic Effects of Whey Compounds in Patients With Diabetes Mellitus Type 2.

Metabolic Effects of Whey Compounds in Patients With Diabetes Mellitus Type 2.

The main objective of our study is to investigate the metabolic effects of a i) ordinary whey protein (WHE) and ii) a specific whey protein fraction (speWHE) when the interventions are ingested by patients with type 2 diabetes 30 minutes prior to an oral glucose tolerance test (OGTT). We will also investigate the glucose response when the patients ingest the interventions at home in their own environment 30 minutes before breakfast and dinner (2days) and also monitor glucose levels without interventions (2 days).

Inclusion Criteria:

• Age > 18 years
• Type 2 diabetes (T2D) diagnosis
• No medical treatment or metformin/sulfonylureas(SU) alone in the treatment of T2D
• No daily use of protein drinks
• Hba1c between 40 mmol/mol and 69 mmol/mol
• 20 kg/m2 < BMI < 35 kg/m2
• Screening blood test: 1200 pmol/l > C-peptid > 370 pmol/l

Exclusion Criteria:

• Other diabetes medication than metformin/SU (e.g. insulin, GLP-1 analog, DPP-4 inhibitor, SGLT2-inhibitor)
• Affected screening blood test assessed by the primary investigator(PI)/sponsor
• Does not understand or speak danish
• Milk allergy
• PI finds the patient not fit (e.g. mental illness, too nervous or other)