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Terminal constipation affects 13 to 20% of the french population. Anismus is defined by an absence of relaxation or a paradoxical contraction of the striated anal sphincter muscle during defecation.
Anismus is one of the main causes of terminal constipation. Anismus diagnosis is retained if 2 out of 3 examinations (manometry, electromyogram, defecography) are positive.
EndoFLIP® is a new medical device developed to measure distensibility of a hollow organ. Anal EndoFLIP® l could be a more sensitive and specific tool for detecting anismus in patients with distal constipation.
60 patients suffering from distal constipation will be included in order to perform, in addition to the usual examinations, an anal EndoFlip in order to test the sensitivity and specificity of this method for the diagnosis of anismus.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Detection of anismus in patients with distal constipation | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Anal EndoFLIP® | Device | Anal EndoFLIP® measure to evaluate anal compliance |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity of the anal distensibility evaluated with the EndoFLIP® technique for the diagnosis of anismus | 30 min | |
| Specificity of the anal distensibility evaluated with the EndoFLIP® technique for the diagnosis of anismus | 30 min |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Laura BRIL, MD | University Hospital, Rouen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rouen University Hospital | Rouen | France |
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| ID | Term |
|---|---|
| D019841 | Defecography |
| D004576 | Electromyography |
| ID | Term |
|---|---|
| D011860 | Radiography, Abdominal |
| D011859 | Radiography |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
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| Anal Manometry | Diagnostic Test | Anal Manometry done in standard care |
|
| Defecography | Diagnostic Test | Defecographydone in standard care |
|
| Electromyogram | Diagnostic Test | Electromyogram done in standard care |
|
| D003933 | Diagnosis |
| D004568 | Electrodiagnosis |
| D009213 | Myography |