Earlier Mobilization Post Acute Thrombectomy

Earlier Mobilization Post Acute Thrombectomy

This is a phase III trial trying to determine whether 12-hour bed rest following thrombectomy for ischemic stroke is non-inferior to 24-hour bed rest by measure of outcomes on the modified Rankin Scale (mRS) at 90 days post bed rest.

Inclusion Criteria:

• Age 18 years or older
• Received thrombectomy (may have also received intravenous tPA) for a diagnosis of acute ischemic stroke
• TICI 2b/2c/3 score following thromectomy
• Patient and/or Legally Authorized Representative provide consent

Exclusion Criteria:

• TICI 0/1/2a score following thrombectomy
• Venous thromboembolism present at symptom onset
• Pneumonia present at symptom onset
• STEMI at symptom onset
• Positive troponins at symptom onset according to local values
• Bone fracture at symptom onset
• Intubation anticipated or occurred
• Symptomatic intracranial hemorrhage (defined as increase in NIHSS by 4 points or more accompanied by PH2 hemorrhage on imaging) at the time of screening.
• Pre-screening systolic blood pressure < 110 mmHg
• Resting pulse oximetry < 92% (with or without supplemental oxygen)
• Neurological worsening (defined as NIHSS increase of 4 points compared to initial score) prior to screening.
• Baseline modified Rankin Scale score > 2
• Known Pregnancy
• Patient not anticipated to survive 3 months
• Patient not anticipated to follow-up at 3 months