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| Name | Class |
|---|---|
| AstraZeneca | INDUSTRY |
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This is a national, multi center, retrospective observational cohort study that will be carried out by reviewing the medical records of patients with relapsed epithelial ovarian, fallopian tube, or peritoneal cancer treated with olaparib following response to platinum-based chemotherapy.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Olaparib | Drug | Patients with histologically confirmed ovarian cancer, primary peritoneal cancer and / or fallopian-tube cancer treated with olaparib in a real life-setting, between May 2014 to March 2017, whatever the line of therapy |
| Measure | Description | Time Frame |
|---|---|---|
| progression free survival (PFS) | PFS (days) = date of progression - date of treatment start + 1 | through study completion, an average of 1 year |
| overall Survival (OS) | OS (days) = date of death - date of treatment start + 1 | through study completion, an average of 1 year |
| incidence of events of clinical interest | the following events: anemia, thrombopenia, nausea and vomiting, fatigue, myelodysplastic syndrome, upper respiratory infections, diarrhea, decreased appetite, dysgeusia and headache will be formally retrieved from the source documents. | through study completion, an average of 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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The patient population observed in this study must fulfil all of the following inclusion criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Thibault de La Motte Rouge, Dr | Centre Eugène Marquis | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ICO Paul Papin | Angers | 49055 | France | |||
| Institut Sainte-Catherine |
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| Avignon |
| 84918 |
| France |
| CHRU Jean Minjoz | Besançon | 25030 | France |
| Clinique Tivoli | Bordeaux | 33000 | France |
| Institut Bergonié | Bordeaux | 33076 | France |
| Clinique Pasteur | Brest | 29200 | France |
| Hôpital Morvan - Centre Hospitalier Universitaire | Brest | 29200 | France |
| Centre Jean Perrin | Clermont-Ferrand | 63000 | France |
| Centre Georges François Leclerc | Dijon | 21079 | France |
| Groupe Hospitalier Mutualiste de Grenoble | Grenoble | 38028 | France |
| Institut Hospitalier Franco-Britannique | Levallois-Perret | 92300 | France |
| Centre Léon Bérard | Lyon | 69373 | France |
| ICM Val d'Aurelle | Montpellier | 34298 | France |
| ORACLE - Centre d'Oncologie de Gentilly | Nancy | 54100 | France |
| Hôpital Privé du Confluent S.A.S. | Nantes | 44277 | France |
| Centre Antoine Lacassagne | Nice | 6189 | France |
| Centre Hospitalier Régional d'Orléans | Orléans | 45067 | France |
| Hôpital Saint-Louis | Paris | 75010 | France |
| Hôpital Cochin | Paris | 75014 | France |
| Institut du Cancer Courlancy Reims | Reims | 51100 | France |
| Centre Eugène Marquis | Rennes | 35042 | France |
| Centre Hospitalier de Saint-Brieuc | Saint-Brieuc | 22015 | France |
| ICO Centre René Gauducheau | Saint-Herblain | 44805 | France |
| Clinique Mutualiste de l'Estuaire, Cité Sanitaire | Saint-Nazaire | 44600 | France |
| Institut de Cancérologie Lucien Neuwirth | Saint-Priest-en-Jarez | 42271 | France |
| Hôpitaux Universitaires de Strasbourg | Strasbourg | 67091 | France |
| ICL Institut de Cancérologie de Lorraine | Vandœuvre-lès-Nancy | 54511 | France |
| Gustave Roussy | Villejuif | 94805 | France |
| ID | Term |
|---|---|
| C531550 | olaparib |
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