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| Name | Class |
|---|---|
| Institut National de la Santé Et de la Recherche Médicale, France | OTHER_GOV |
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In patients aged 75 years and older, polypathology is frequent and often associated with polypharmacy. This polypharmacy coupled with a lack of proactive elderly care can sometimes lead to hospitalisation. Due to comorbidities and complex problems, management of geriatric patients usually requires a multidisciplinary approach. In Toulouse University Hospital, elderly inpatients can benefit from a geriatric assessment by a Geriatric Mobile Team. Whether this team improve the prescriptions through the advice of a clinical pharmacist has not been demonstrated yet.
All participants will be identified via the geriatrician of the mobile geriatric team with the following inclusion criteria: age ≥ 75 years, ≥ 5 medications per day and being hospitalised either in emergency room, short-stay medicine unit or in a surgery department. For each patient, the pharmacist will detect potentially inappropriate prescribing (based on explicit criteria and an implicit approach) and liaise with the geriatrician for drug optimisations. The pharmaceutical advice will be added to the geriatrician's written report, and then addressed to the relevant physician. The implementation of the proposals will be evaluated immediately at the end of hospitalisation, and then reassessed three months later by calling the patient and/or his community pharmacist. A total of 250 patients will be enrolled over a 12 month-period. The evolution of potentially inappropriate prescribing will be assessed and their cost evaluated.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Medication therapy management | Experimental | Medication therapy management by pharmacist-led medication review |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Medication therapy management | Other | The intervention is in the form of a pharmacist-led medication review aimed at detecting potentially inappropriate prescribing. It includes:
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline patients' number of potentially inappropriate prescription at the patient discharge after optimization by a mobile geriatric team with pharmacist | number of potentially inappropriate prescribing per patient before (month 0) and after the intervention of the mobile geriatric team (at the patient discharge) | Month 0 and max Month 2 (At the patient discharge) |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline patients' number of potentially inappropriate prescription at 3 months after optimization by a mobile geriatric team with pharmacist | number of potentially inappropriate prescribing per patient before (month 0) and after the intervention of the mobile geriatric team (month 3) | Month 0, Month 3 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Philippe CESTAC, PharmD, PhD | University Hospital, Toulouse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Toulouse University Hospital | Toulouse | Occitanie | 31059 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33268421 | Background | Pages A, Roland C, Qassemi S, Abdeljalil AB, Houles M, Romain M, Toulza O, Belloc A, McCambridge C, Voisin T, Cestac P, Juillard-Condat B; PharMoG study group. Impact of a Pharmacist-included Mobile Geriatrics team intervention on potentially inappropriate drug prescribing: protocol for a prospective feasibility study (PharMoG study). BMJ Open. 2020 Dec 2;10(12):e040917. doi: 10.1136/bmjopen-2020-040917. | |
| 41862799 |
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| ID | Term |
|---|---|
| D054539 | Medication Therapy Management |
| ID | Term |
|---|---|
| D010593 | Pharmaceutical Services |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
| D054524 | Medicare Part D |
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|
| Change from baseline patients' number with at least one potentially inappropriate drug at 3 months after optimization by a mobile geriatric team with pharmacist |
number of patients with at least one potentially inappropriate drug before (month 0) and after the intervention of the mobile geriatric team (month 3) |
| Month 0, Month 3 |
| Change from baseline ratio of potentially inappropriate drug per patient at 3 months after optimization by a mobile geriatric team with pharmacist | ratio of potentially inappropriate drug per patient before (month 0) and after (month 3) the intervention of the mobile geriatric team. | Month 0, Month 3 |
| Change from baseline mean number of medications per patient at 3 months | Mean number of medications per patient | Month 0, Month 3 |
| realisation of a pharmacist-led medication review in primary care | Number of pharmacist-led medication review performed in primary care at 3 months | Month 3 |
| number of falls 3 months after pharmacist-led medication review | Number of falls | Month 3 |
| mortality 3 months after pharmacist-led medication review | Number of deaths | Month 3 |
| re-hospitalisation, including emergency room transfers | Number of non-scheduled hospitalisations (including emergency department transfers) | Month 3 |
| The nursing home transfers | Number of nursing home transfers | Month 3 |
| Derived |
| Dintilhac A, Qassemi S, Roland C, McCambridge C, Abdeljalil AB, Houles M, Romain M, Toulza O, Dunet C, Belloc A, Strumia M, Cestac P, Voisin T, Juillard-Condat B. The impact of an intervention by a mobile geriatrics team including a pharmacist on potentially inappropriate drug prescription: results of the PharMoG study. BMC Geriatr. 2026 Mar 21;26(1):598. doi: 10.1186/s12877-026-07366-1. |
| D007356 | Insurance, Pharmaceutical Services |
| D007348 | Insurance, Health |
| D007341 | Insurance |
| D005381 | Financing, Organized |
| D004467 | Economics |
| D004472 | Health Care Economics and Organizations |
| D006278 | Medicare |
| D010346 | Patient Care Management |
| D006298 | Health Services Administration |