The Efficacy of Clenpiq utilized per FDA labeling, with a low residue diet the day before colonoscopy.

This study proposes to assess the use of a low residue diet of a prescribed nature the day before colonoscopy for breakfast, lunch and early dinner. Clinical outcomes utilizing the low residue diet will be compared to the Food and Drug Administration (FDA) approved split dose labeling, including the traditional clear liquid diet the day before colonoscopy utilizing the Clenpiq (Ferring Pharmaceuticals) bowel preparation.

Inclusion Criteria:

• All subjects age 18-80 requiring colonoscopy for appropriate indications

Exclusion Criteria:

• Active diarrhea (Greater than 3 unformed stools daily)
• Constipation (Less than 3 spontaneous bowel movements per week) Each within 2 weeks of the scheduled Colonoscopy.

Additional exclusion criteria would include;

• Subjects with a history of inflammatory bowel disease
• Colonic resection of any length
• Pregnant women
• American Society of Anesthesiologists (ASA) score greater than 3
• Body Mass Index (BMI) greater than 50
• Previous reaction to this bowel preparation or contraindications to taking Clenpiq per the package labeling guidelines.
• Subjects unable to give their own informed consent.

Investigator will be ignorant of how preparation was taken