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| Name | Class |
|---|---|
| University College of Southeast Norway | OTHER |
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The aim of this study is to investigate the effects of task shifting from anesthesiologists to special trained nurses performing femoral nerve block (FNB) in patients with hip fracture in the emergency department (ED) at Vestfold Hospital Trust (VHT). A sample of nurses (n= 6) will perform ultrasound guided FNB in hip fracture patients (n=25) admitted to the ED at VHT. This cohort will be compared to another cohort of hip fracture patients (n=25). This cohort will follow standard of care where the femoral nerve block is often performed by anesthesiologists. The study is a prospective, controlled randomized trial.
The ageing population admitted to the ED in developed countries is steadily increasing. Hip fractures are common among the elderly population, and related to increased mortality. Patient satisfaction with ED's has been an international challenge over several years. Acute pain is one of the most common reasons for patients coming admitted to the ED. However, undertreatment of pain is common, particularly in patients with hip fractures.
Pain control can be difficult, and often requires intensive nursing and physician care, as elderly patients may manifest cardiovascular and respiratory complications from opioid administration. Optimizing acute pain management in patients with orthopedic trauma is important and can translate into significant positive physiologic and financial outcomes.
At Vestfold Hospital Trust, pain relief of the hip fracture patient in ED has traditionally most often consisted of paracetamol and opiates. Additionally, the patients are offered FNB by the anesthesiologist, but concurrent conflicts and other organizational circumstances has have led to delayed block or no block for all or some patients. This often necessitate a continuation of pain relief in form of intravenous opioids, with increased risk of opioid side effects such as respiratory depression, delirium, constipation, urinary retention, nausea and vomiting and subsequently increased morbidity and increased costs for the hospital and the community.
The investigators believe that shifting this task to nurses working in the ED can secure patient with hip fractures sufficiently and timely pain relief. By giving trained nurses this new task of performing FNB the investigators can study how expert nurses qualifications' are utilized to strengthen the quality of the ED. This study aims to implement and evaluate the introduction of specially trained nurses performing ultrasound guided FNB in patients with hip fractures in the ED. This implementation may be beneficial to patients in terms of prompt analgesia, reduced opioid consumption, thereby reducing opioid adverse events, and it might influence risk of complications and length of stay. The aim of this study is to evaluate cumulative Numeric Rating Scale (NRS) score during rest and during passive movement (30 degree flexion in the hip) in patients with hip fracture during stay in the ED at 120 minutes after admission, thereby comparing nurse-led FNB versus standard of care.
The study has a randomized controlled trial design. Patients are randomized (1:1) into two groups:
Hypothesis: A single shot FNB performed by nurses in the ED compared to todays practice will result in lower cumulative NRS score first 120 minutes after admission to ED than current practice.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nurse-led femoral nerve block | Experimental | Trained nurses in ED provide ultrasound guided single-shot femoral nerve block shortly after (at arrival emergency department) the patient is diagnosed with a hip fracture. Drug: Ropivacaine 3 mg/kg, single-shot |
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| Standard of care | Active Comparator | Nurses do not provide ultrasound guided single-shot FNB and the patient follows the standard of care course. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nurse-led femoral nerve block | Procedure | The nurse perform a femoral nerve block in the emergency department in patients diagnosed with a hip fracture (x-ray) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cumulative dynamic pain score - Numerical Rating Scale (NRS) - during passive movement at 120 minutes after start of procedure | Cumulative dynamic pain score - Numerical Rating Scale (NRS) - during passive movement (30 degree flexion in the fractured hip) in patients with hip fracture during stay in the ED at 120 minutes after admission, measured by five time Points; At the end of procedure, 30 min.-, 60 min.-, 90 min.- and 120 min after start of procedure. NRS score: 0 is no pain and 10 is the worst pain. | 120 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Number of total morphine equivalents - 24h | Number of total morphine equivalents, mg (iv/po) administered during first 24 hours from admission at the emergency department | 24 hours |
| Number of total morphine equivalents - Hospital stay |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of delirium during hospital stay. | Incidence of delirium, measured by Assessment test for delirium & cognitive impairment - 4AT, will be performed daily during hospital stay, number of patients | Approx. 6 days |
| RASS-score - Richmond Agitation and Sedation Scale |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Elin Saga, nurse | The Hospital of Vestfold | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sykehuset i Vestfold HF | Tønsberg | 3103 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38070309 | Derived | Saga E, Falk RS, Bing-Jonsson PC, Skovdahl KI, Lindholm E. Nurse-led ultrasound-guided femoral nerve block: A randomised controlled trial of two different patient flow systems in an emergency department. Int J Orthop Trauma Nurs. 2024 Feb;52:101074. doi: 10.1016/j.ijotn.2023.101074. Epub 2023 Dec 4. | |
| 33238043 | Derived |
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| ID | Term |
|---|---|
| D006620 | Hip Fractures |
| D005265 | Femoral Neck Fractures |
| ID | Term |
|---|---|
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D025981 | Hip Injuries |
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Prospective, randomized, controlled, open label trial
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Number of total morphine equivalents, mg (iv/po) administered during total hospital stay.
| approx. 6 days |
| Cumulative rest pain score -Numerical Rating Scale (NRS) - at 120 minutes after start of procedure | Cumulative rest pain score NRS - Numerical Rating Scale (NRS) - in patients with hip fracture during stay in the emergency department at 120 minutes after admission, measured by five time Points; At the end of procedure, 30 min.-, 60 min.-, 90 min.- and 120 min after start of procedure. NRS score: 0 is no pain and 10 is the worst pain. | 120 minutes |
Measure consciousness assessed by RASS-score - Richmond Agitation and Sedation Scale - (at admittance to the emergency department and daily). Total score. RAAS is a10-point scale, with four levels of anxiety or agitation (+1 to +4), one level to denote a calm and alert state (0), and 5 levels of sedation (-1 to -5) culminating in unarousable (-5). |
| Daily - approx. 6 days |
| Number of (mg) administered of antiemetics during hospital stay | Number of (mg) administered of antiemetics ( ondansetron, dexagalen, metoclopramide) during first 24 hours and during hospital stay. | approx. 6 days |
| Time (minutes) to perform an ultrasound guided femoral nerve block performed | Time (minutes) used to perform an ultrasound guided femoral nerve block performed by nurses. | approx 30 minutes |
| Time from arrival at the emergency department to femoral nerve block is performed | Time (min.) from arrival at emergency department (from Radiological Department) to femoral nerve block is performed. | Approx 1 hour |
| Time from admission to surgery starts | Time from admission to surgery starts, minutes | approx. 48 hours |
| Length of total hospital stay | Length of total hospital stay, days | Approx. 6 days |
| Mortality during hospitalization | Mortality during hospitalization, Yes or no | Approx. 6 days |
| Mortality 30 days | Mortality at postoperative day 30, Yes or no | 30 days |
| Hospital acquired pneumonia | Hospital acquired pneumonia during hospital stay, Yes or no | Approx 6 days |
| Acute myocardial infarction | Acute myocardial infarction during hospital stay, Yes or no | Approx 6 days |
| Acute renal failure | Acute renal failure during hospital stay, Yes or no | Approx 6 days |
| Respiratory failure | Respiratory failure during hospital stay, Yes or no | Approx 6 days |
| Intravasal injection | Intravasal injection - visually + circulatory and neurological symptoms, Yes or no | 24 hours |
| Hematoma | Hematoma - defined as a new tumor > 2 centimeter in the groin / injection site measured by ultrasound, Yes or no | 24 hours |
| Neurologic systemic outcomes / symptoms / paresthesia | Neurologic systemic outcomes / symptoms / paresthesia that have occurred after admission and which persist until discharge, numbers | Approx 6 days |
| Guay J, Kopp S. Peripheral nerve blocks for hip fractures in adults. Cochrane Database Syst Rev. 2020 Nov 25;11(11):CD001159. doi: 10.1002/14651858.CD001159.pub3. |
| D007869 |
| Leg Injuries |