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This study aims to investigate the potential association between pain sensitivity questionnaire score, the severity of postoperative pain, and postoperative analgesic requirement in patients with open colorectal cancer surgery. This information may be used to guide the optimal postoperative pain management, and ultimately improve patient's quality of life.
We plan to investigate the predictive ability of the PSQ as well as experimental parameters of pain sensitivity using electronic algometer and other known risk factors for postoperative pain in 100 patients scheduled for open colorectal cancer surgery.
The following items are investigated before surgery; Age, sex, level of education, type of surgery, past surgical history, presence of chronic pain, the expected maximal pain score (VAS) after surgery, Pain catastrophizing scale, anxiety scale (HADS-A), Pain sensitivity questionnaire, and pain threshold measured by electronic algometer.
The total opioid consumption is investigated for 24 and 48 hours after surgery. In addition, the severity of postoperative pain is measured by the 11-point VAS at 24 and 48 hours after surgery. Patient satisfaction with postoperative pain control is also investigated at 48 hours after surgery using the 7-point patient's satisfaction scale.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| study group | Experimental | The following tests will be performed on the study subjects.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electronic digital pressure algometer | Device | Evaluation of pain threshold using an algometer is conducted one day before surgery. The pressure of the plunger of algometer is applied vertically to the patient's right thenar muscle belly at a speed of 10 N/sec by the tester. Then the tester removes the algometer when the patients start to feel pain and record the pressure recorded on the algometer. |
| Measure | Description | Time Frame |
|---|---|---|
| Total fentanyl consumption during 24 hours | postoperative fentanyl consumption (mcg) via IV patient controlled analgesia | postoperative 24 hours |
| Total fentanyl consumption during 48 hours | postoperative fentanyl consumption (mcg) via IV patient controlled analgesia | postoperative 48 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative pain score | 11-pointed NRS pain score at resting/coughing/movement NRS (0-10): 0, "no pain"; 10, "worst pain imaginable" | postoperative 24, 48 hours |
| Patient satisfaction for postoperative pain management |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jintae Kim, MD, PhD | Contact | 82-2-2072-3295 | jintae73@gmail.com | |
| Hojin Lee, MD | Contact | 82-2-2072-2467 | zenerdiode03@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Jintae Kim, MD, PhD | Seoul National University Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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Prospective observational study
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| Pain sensitivity questionnaire | Diagnostic Test | Evaluation of pain threshold using the Korean-version pain sensitivity questionnaire is conducted one day before surgery. |
|
7-pointed likert scale (very satisfied-somewhat satisfied-satisfied-neutral-dissatisfied-somewhat dissatisfied-very dissatisfied)
| postoperative 48 hours |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |