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To compare bipolar resection versus holmium laser enucleation for management of large BPH.
To compare safety and efficacy of bipolar resection (BPRP) versus holmium laser enucleation (HoLEP) for management of large BPH (> 75 gm).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| holmium laser enucleation of the prostate | Active Comparator | holmium laser enucleation of the prostate (HoLEP) |
|
| bipolar resection of the prostate | Active Comparator | bipolar resection of the prostate (BPEP) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| holmium laser enucleation of the prostate | Procedure | cystoscopic transurethral enucleation of the prostate using Holmium laser (Versa pulse 100W; Lumenis; Germany) |
|
| Measure | Description | Time Frame |
|---|---|---|
| hemoglobin drop postoperatively (gm/dL) | difference in hemoglobin concentration postoperatively vs preoperatively | Immediate postoperatively |
| operative duration in minutes | operative duration | during surgery |
| Hospital stay in days | Hospital stay | immediately after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| complications (%) | intraoperative and postoperative complications including blood transfusion, capsular perforation, irritative symptoms, SUI, urethral stricture, bladder neck contracture, urinary retention. | Two years |
| urine flow |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| enmar I Habib | Cairo University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University Hospitals | Cairo | 12222 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32842769 | Derived | Habib EI, ElSheemy MS, Hossam A, Morsy S, Hussein HA, Abdelaziz AY, Abdelazim MS, Fathy H. Holmium Laser Enucleation Versus Bipolar Plasmakinetic Resection for Management of Lower Urinary Tract Symptoms in Patients with Large-Volume Benign Prostatic Hyperplasia: Randomized-Controlled Trial. J Endourol. 2021 Feb;35(2):171-179. doi: 10.1089/end.2020.0636. Epub 2020 Oct 29. |
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|
| Bipolar resection of the prostate | Procedure | cystoscopic transurethral resection of the prostate using bipolar energy |
|
|
Qmax (ml/s),
| Two years |
| post-voiding residual urine | postvoiding residual urine (ml) | Two years |
| International prostate symptom score (IPSS) | an international commonly used score ranging from 0 - 35 (the worst is 35) evaluating voiding and storage urinary symptoms using 7 questions each one is scored from 0 to 5 according to severity of symptom | Two years |
| Quality of life (QoL) | section of International prostate symptom score (IPSS) one question scored from 0 up to 6 (6 is worst) | Two years |
| Catheter duration | Catheter duration in hours | immediate postoperatively |