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This study will be undertaken to determine whether the frequency of fetal surveillance can be safely reduced from bi-weekly to weekly in the case of fetusus with intrauterine growth restriction.
In this prospective randomized study, the cases whose fetal weight predicted by ultrasonography (USG) between the 28th and 37th weeks of gestation are below 10percentile according to the World Health Organization (WHO) normograms. The cases will be divided into two groups as group 1:weekly and group 2:bi-weekly (twice-weekly) The cases will be evaluated by fetal Doppler, amniotic fluid volume, nonstress test (NST) and maternal preeclampsia tests.Maternal severe hypertension/preeclampsia, category 3 NST, oligohydramnios (after 37 weeks amniotic fluid index <5; after 34 weeks single deepest pocket <2 cm) ,pathological doppler (before 34 weeks reverse flow in an umbilical artery , after 34 weeks absent end-diastolic flow in an umbilical artery) in cases of birth decision will be taken. Cases without the above mentioned complications will be delivered between 38 weeks 3 days and 39 weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| weekly | Experimental | weekly fetal surveillance |
|
| bi-weekly (twice-weekly) | Active Comparator | bi-weekly fetal surveillance |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| weekly | Procedure | fetal surveillance frequency |
| |
| bi-weekly |
| Measure | Description | Time Frame |
|---|---|---|
| neonatal hospital stay | duration of neonatal hospital stay (days) | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| antenatal hospital stay | duration of antenatal hospital stay (days) | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| gestational age at delivery | gestational age at delivery as days (e.g. 261days) | 24 hours |
| neonatal hospital stay | duration of neonatal hospital stay (days) |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| taha takmaz, MD | Contact | +902124531700 | thtkmz@hotmail.com | |
| serdar kutuk, MD | Contact | +902124531700 | mehmetserdarkutuk@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bezmialem Vakıf University Hospital | Recruiting | Istanbul | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D005317 | Fetal Growth Retardation |
| ID | Term |
|---|---|
| D005315 | Fetal Diseases |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| Procedure |
fetal surveillance frequency |
|
| 3 months |
| acidosis | fetal acidosis (normal cord-blood pH ranges from 7.14 to 7.4 during labor, values below 7.14 are considered to be acidosis) | 24 hours |
| perinatal death | The number of perinatal deaths. Perinatal death is a fetal death (stillbirth) or an early neonatal death (first 24 hours after birth) | 3 months |
| cesarean delivery | The number of births by cesarean section | 24 hours |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D006130 | Growth Disorders |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |