Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Internal limiting membrane peeling is performed during vitrectomy for macular diseases such as macular holes, macular edema due to diabetic retinopathy and retinal vein occlusion.
The incidence of epiretinal membrane formation after vitrectomy for rhegmatogenous detachment has been reported to range from 4.4% to 12.8%.
In this study, the efficacy and safety of internal limiting membrane peeling will be studied in vitrectomy for rhegmatogenous retinal detachment and if it is essential to peel it in those cases or not.
interventional observational study comparing vitrectomy with versus without internal limiting membrane peeling in cases of rhegmatogenous retinal detachment.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non-ILM peeling group | Other | vitrectomy without ILM peeling is done to all cases |
|
| ILM peeling group | Other | vitrectomy with ILM peeling is done to all cases |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pars Plana Vitrectomy | Other | vitrectomy with and without ILM peeling |
|
| Measure | Description | Time Frame |
|---|---|---|
| anatomical outcome | Rate of retinal reattachment using indirect ophthalmoscopy | 6 months follow up |
| epiretinal membrane | incidence rate of epiretinal membrane formation after surgery in % percent | 6 months follow up |
| Measure | Description | Time Frame |
|---|---|---|
| functional outcome | visual functions using log Mar Best Corrected Visual Acuity (BCVA) | 6 months follow up |
| superficial capillary density | measurement of percent (%) of superficial and deep capillary density using Optical Coherance Tomography Angiography |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Mohamed F Othman, MD | sub-investigator | Principal Investigator |
| Ahmed Shawkat, MD | sub-investigator | Principal Investigator |
| khalid Murad | sub-investigator | Principal Investigator |
| Mohamed Abdullah | sub-investigator | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Minia UNiversity hospital | Minya | Minya Governorate | 61111 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32411388 | Derived | Abdullah ME, Moharram HEM, Abdelhalim AS, Mourad KM, Abdelkader MF. Evaluation of primary internal limiting membrane peeling in cases with rhegmatogenous retinal detachment. Int J Retina Vitreous. 2020 May 7;6:8. doi: 10.1186/s40942-020-00213-4. eCollection 2020. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 20, 2020 | |
| Reset | Mar 4, 2020 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 20, 2020 | Mar 4, 2020 |
| ID | Term |
|---|---|
| D012163 | Retinal Detachment |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 6 months follow up |
| multi-focal Electroretinogram | measurement of P1 amplitude | 6 months follow up |