Testicular Function After Testicular Torsion

Testicular Function After Testicular Torsion

The purpose of this study is to evaluate testicular function measured as testosterone level and semen quality.

Men having undergone surgery for testicular torsion between 01.01.2003 - 12.31.2012 will receive a invitation to participate in this study. It is expected that 110 patients can be identified and about 65% of them will participate. These men will undergo a andrological evaluation, deliver a semen sample, have a blood sample taken and undergo a testicular ultrasound.

Control group:

Men attending the fertility counseling at Herlev hospital will be offered participation in this study. The fertility counseling demands that men who contact the clinic have never had their sperm analyzed, have not tried to get pregnant with their partner for more than a year and that they have no prior knowledge of their fertility.

Primary endpoint:

• Semen quality measured as sperm concentration
• Total testosterone level

Secondary endpoint:

Semen parameters

• Semen volume (ml)
• Sperm concentration (x 106/ml)
• Sperm motility (%) (både klasse AB og ABC)
• sperm morphology
• IgA-bound spermatozoa (%)
• IgG-bound spermatozoa (%)

Hormones

• FSH
• LH
• PRL
• Testosterone
• Estradiol
• Inhibin B
• Insulin-like peptide 3
• SHBG

Data points:

• Paternity
• Time to pregnancy
• Partner (yes/no)
• Any fertility treatment?
• Pain? (VAS score)
• Symptoms of testesterone deficiency symptoms
• Andrological evaluation
• Testicular ultrasound
• Testicular torsion events in the family
• Date of surgery
• Date of follow up meeting
• Surgery details

Inclusion Criteria:

• Men with a verified testicular torsion operated at Herlev and Gentofte hospital between 01.01.2003 and 12.31.2012

Exclusion Criteria:

• Retentio testis
• Varicocele
• Previous treatment with chemo- or radiation therapy
• Genetic disposition for infertility
• Anejculation
• Retrograde ejaculation